Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Acel_0622PFAM: peptidylprolyl isomerase, FKBP-type; KEGG: sma:SAV6686 FK-506 binding protein, peptidyl-prolyl cis-trans isomerase. (386 aa)    
Predicted Functional Partners:
Acel_2012
KEGG: tfu:Tfu_0043 aspartate kinase; TIGRFAM: aspartate kinase; aspartate kinase, monofunctional class; PFAM: aspartate/glutamate/uridylate kinase; amino acid-binding ACT domain protein; Belongs to the aspartokinase family.
    
   0.608
Acel_0402
SMART: Pyrrolo-quinoline quinone; KEGG: spn:SP1772 cell wall surface anchor family protein.
   
   0.607
infA
Bacterial translation initiation factor 1 (bIF-1); One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.
   
   0.599
Acel_0620
TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; KEGG: ade:Adeh_1576 diguanylate cyclase (GGDEF domain).
       0.545
Acel_0621
KEGG: cyb:CYB_0085 hypothetical protein.
       0.545
dnaK
Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.
   
 0.502
Acel_1277
PFAM: Fmu (Sun) domain protein; NusB/RsmB/TIM44; KEGG: sma:SAV6878 putative RNA-binding Sun protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
 
   0.501
Acel_0367
TIGRFAM: IMP dehydrogenase family protein; KEGG: tfu:Tfu_2595 IMP dehydrogenase related 2.
 
 
 0.497
Acel_0012
Peptidylprolyl isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family.
  
 0.485
Acel_1703
KEGG: sco:SCO2947 hypothetical protein.
  
     0.450
Your Current Organism:
Acidothermus cellulolyticus
NCBI taxonomy Id: 351607
Other names: A. cellulolyticus 11B, Acidothermus cellulolyticus 11B, Acidothermus cellulolyticus str. 11B, Acidothermus cellulolyticus strain 11B
Server load: low (12%) [HD]