Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Acel_0638PFAM: UDP-N-acetylglucosamine 2-epimerase; KEGG: mth:MTH837 UDP-N-acetylglucosamine 2-epimerase; Belongs to the UDP-N-acetylglucosamine 2-epimerase family. (381 aa)    
Predicted Functional Partners:
glmU
UDP-N-acetylglucosamine pyrophosphorylase / glucosamine-1-phosphate N-acetyltransferase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain.
    
 0.927
Acel_0408
PFAM: UDP-glucose/GDP-mannose dehydrogenase; KEGG: tfu:Tfu_2544 UDP-glucose 6-dehydrogenase.
    
 0.909
murA
UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily.
  
 
  0.907
murA-2
UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily.
  
 
  0.907
Acel_0644
PFAM: glycosyl transferase, family 4; KEGG: sma:SAV2907 putative teichoic acid linkage unit synthesis (synthesis of undecaprenylpyrophosphate-N-aetylglucosamine).
  
 0.894
Acel_0166
UDP-glucose pyrophosphorylase; TIGRFAM: UTP-glucose-1-phosphate uridylyltransferase; PFAM: Nucleotidyl transferase; KEGG: sma:SAV3673 putative UTP-glucose-1-phosphate uridylyltransferase.
  
 
 0.865
Acel_1231
Nucleotidyltransferase; PFAM: transferase hexapeptide repeat containing protein; Nucleotidyl transferase; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain II; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain III; KEGG: tfu:Tfu_1394 mannose-1-phosphate guanylyltransferase.
    
 0.847
Acel_0413
TIGRFAM: glucose-1-phosphate thymidyltransferase; PFAM: Nucleotidyl transferase; KEGG: fra:Francci3_0713 glucose-1-phosphate thymidyltransferase.
  
 
 0.836
Acel_0451
Nucleotidyltransferase; PFAM: transferase hexapeptide repeat containing protein; Nucleotidyl transferase; KEGG: fra:Francci3_0737 nucleotidyl transferase.
    
 0.814
Acel_0637
PFAM: protein of unknown function DUF201; KEGG: cac:CAC2189 hypothetical protein.
     
 0.790
Your Current Organism:
Acidothermus cellulolyticus
NCBI taxonomy Id: 351607
Other names: A. cellulolyticus 11B, Acidothermus cellulolyticus 11B, Acidothermus cellulolyticus str. 11B, Acidothermus cellulolyticus strain 11B
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.