STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Acel_0693PFAM: Methionine synthase, vitamin-B12 independent; KEGG: tfu:Tfu_0602 hypothetical protein. (344 aa)    
Predicted Functional Partners:
Acel_0991
KEGG: fra:Francci3_1389 5,10-methylenetetrahydrofolate reductase; TIGRFAM: 5,10-methylenetetrahydrofolate reductase; PFAM: methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family.
  
 0.893
metK
Methionine adenosyltransferase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
  
 0.821
ahcY
Adenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.
  
 
 0.782
Acel_1371
PFAM: ErfK/YbiS/YcfS/YnhG family protein; KEGG: fra:Francci3_1911 ErfK/YbiS/YcfS/YnhG.
  
     0.747
Acel_1521
PFAM: GCN5-related N-acetyltransferase; KEGG: fra:Francci3_3572 GCN5-related N-acetyltransferase.
  
     0.740
Acel_1174
Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
  
  
 0.731
Acel_0882
KEGG: tfu:Tfu_1965 hypothetical protein.
  
     0.724
Acel_0218
KEGG: fra:Francci3_3498 putative Lsr2-like protein.
  
     0.660
Acel_0462
KEGG: fra:Francci3_0749 hypothetical protein.
  
     0.629
Acel_2134
KEGG: sma:SAV4293 transmembrane protein.
  
     0.602
Your Current Organism:
Acidothermus cellulolyticus
NCBI taxonomy Id: 351607
Other names: A. cellulolyticus 11B, Acidothermus cellulolyticus 11B, Acidothermus cellulolyticus str. 11B, Acidothermus cellulolyticus strain 11B
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.