Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Acel_0726PFAM: NADH/Ubiquinone/plastoquinone (complex I); KEGG: rfr:Rfer_3292 NADH dehydrogenase (quinone). (684 aa)    
Predicted Functional Partners:
Acel_0728
PFAM: NADH-ubiquinone oxidoreductase, chain 49kDa; NADH dehydrogenase (ubiquinone), 30 kDa subunit; KEGG: dsy:DSY3115 formate hydrogenlyase subunit 5 precursor.
 
 
 0.999
Acel_0727
PFAM: NADH ubiquinone oxidoreductase, 20 kDa subunit; KEGG: ade:Adeh_3660 NADH ubiquinone oxidoreductase, 20 kDa subunit.
 
 
 0.991
Acel_0731
PFAM: respiratory-chain NADH dehydrogenase, subunit 1; KEGG: sso:SSO1026 formate hydrogenlyase subunit 4 (HycD).
 
 
 0.981
Acel_0730
KEGG: mca:MCA1140 hydrogenase subunit.
 
  
 0.967
Acel_0278
KEGG: sma:SAV4848 putative NADH dehydrogenase chain L; TIGRFAM: proton-translocating NADH-quinone oxidoreductase, chain L; PFAM: NADH-Ubiquinone oxidoreductase (complex I), chain 5/L domain protein; NADH/Ubiquinone/plastoquinone (complex I).
 
 
0.943
Acel_0729
NADH dehydrogenase (quinone); PFAM: NADH/Ubiquinone/plastoquinone (complex I); KEGG: eca:ECA1242 NADH dehydrogenase subunit N.
 
    
0.840
Acel_0724
PFAM: major facilitator superfamily MFS_1; KEGG: gme:Gmet_0906 major facilitator superfamily MFS_1.
 
     0.621
nuoI
NADH dehydrogenase subunit I; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
  
 
 0.601
Acel_0734
SMART: DNA mismatch repair protein MutS domain protein; KEGG: tte:TTE1906 MutS-like ATPase involved in mismatch repair, family 2.
  
     0.584
Acel_0735
PFAM: DNA mismatch repair protein MutS domain protein; KEGG: tvo:TVN0675 MutS-like ATPase involved in mismatch repair.
  
     0.580
Your Current Organism:
Acidothermus cellulolyticus
NCBI taxonomy Id: 351607
Other names: A. cellulolyticus 11B, Acidothermus cellulolyticus 11B, Acidothermus cellulolyticus str. 11B, Acidothermus cellulolyticus strain 11B
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.