Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Acel_0772TIGRFAM: degV family protein; PFAM: DegV family protein; KEGG: sco:SCO2569 hypothetical protein. (283 aa)    
Predicted Functional Partners:
Acel_1581
PFAM: Dak phosphatase; KEGG: sco:SCO5565 hypothetical protein.
 
 0.994
leuS
TIGRFAM: leucyl-tRNA synthetase; KEGG: tfu:Tfu_2156 leucyl-tRNA synthetase bacterial/mitochondrial, class Ia; Belongs to the class-I aminoacyl-tRNA synthetase family.
     
 0.824
Acel_0770
Hypothetical protein.
       0.615
Acel_0775
TIGRFAM: DNA polymerase III, delta subunit; PFAM: DNA polymerase III, delta; KEGG: tfu:Tfu_0823 DNA polymerase III, delta subunit.
  
    0.559
Acel_0773
PFAM: helix-hairpin-helix motif; SMART: Helix-hairpin-helix DNA-binding, class 1; KEGG: nfa:nfa13820 putative DNA-binding protein.
       0.553
Acel_0774
PFAM: ComEC/Rec2-related protein; KEGG: fra:Francci3_1258 ComEC/Rec2-related protein.
       0.553
Acel_0769
FO synthase subunit 1 / FO synthase subunit 2; KEGG: fra:Francci3_0745 conserved hypothetical protein; TIGRFAM: conserved hypothetical protein; PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB.
       0.457
pgk
Phosphoglycerate kinase / triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family.
     
 0.428
disA
Protein of unknown function DUF147; Participates in a DNA-damage check-point. DisA forms globular foci that rapidly scan along the chromosomes searching for lesions.
  
    0.416
Your Current Organism:
Acidothermus cellulolyticus
NCBI taxonomy Id: 351607
Other names: A. cellulolyticus 11B, Acidothermus cellulolyticus 11B, Acidothermus cellulolyticus str. 11B, Acidothermus cellulolyticus strain 11B
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