STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
fliWProtein of unknown function DUF180; Acts as an anti-CsrA protein, binds CsrA and prevents it from repressing translation of its target genes, one of which is flagellin. Binds to flagellin and participates in the assembly of the flagellum. (145 aa)    
Predicted Functional Partners:
csrA
Carbon storage regulator, CsrA; A translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Usually binds in the 5'- UTR at or near the Shine-Dalgarno sequence preventing ribosome-binding, thus repressing translation. Its main target seems to be the major flagellin gene, while its function is anatagonized by FliW.
 
 
 0.994
Acel_0831
TIGRFAM: flagellar hook-associated protein 3; PFAM: flagellin domain protein; KEGG: bsu:BG11936 flagellar hook-associated protein 3 (HAP3).
 
 
 0.973
flgK
TIGRFAM: flagellar hook-associated protein FlgK; PFAM: flagellar basal body rod protein; protein of unknown function DUF1078 domain protein; KEGG: mta:Moth_0746 flagellar hook-associated protein.
 
  
 0.939
Acel_0834
Flagellin domain protein; Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
 
 
 0.913
Acel_0836
PFAM: flagellar protein FliS; KEGG: lxx:Lxx06280 flagellar-like protein.
 
  
 0.908
Acel_0854
PFAM: flagellar motor switch protein FliM; KEGG: lic:LIC11836 flagellar switch protein.
 
  
 0.871
Acel_0835
Flagellar hook-associated 2 domain protein; Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end.
  
  
 0.768
Acel_0839
PFAM: protein of unknown function DUF1078 domain protein; KEGG: lxx:Lxx06310 flagellar basal-body rod protein.
 
 
 0.741
Acel_0833
Hypothetical protein.
 
     0.702
Acel_0848
PFAM: flagellar hook capping protein; KEGG: chy:CHY_0999 flagellar hook assembly protein.
 
  
 0.692
Your Current Organism:
Acidothermus cellulolyticus
NCBI taxonomy Id: 351607
Other names: A. cellulolyticus 11B, Acidothermus cellulolyticus 11B, Acidothermus cellulolyticus str. 11B, Acidothermus cellulolyticus strain 11B
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.