Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Acel_0879Transcriptional regulator, CdaR family; KEGG: sco:SCO2386 hypothetical protein. (384 aa)    
Predicted Functional Partners:
Acel_0878
(acyl-carrier-protein) S-malonyltransferase-like protein; KEGG: fra:Francci3_3481 S-malonyltransferase.
 
     0.861
fabH
3-oxoacyl-[acyl-carrier-protein] synthase III; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids; Belongs to the thiolase-like superfamily. FabH family.
 
     0.632
Acel_0288
KEGG: sco:SCO4636 hypothetical protein; Belongs to the UPF0336 family.
  
     0.591
Acel_1613
PFAM: thioesterase superfamily protein; KEGG: sco:SCO2676 hypothetical protein.
  
   
 0.540
Acel_0289
PFAM: MaoC domain protein dehydratase; KEGG: sco:SCO4637 hypothetical protein.
  
     0.508
Acel_0880
KEGG: fra:Francci3_3058 hypothetical protein.
       0.498
acpP
Phosphopantetheine-binding protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis; Belongs to the acyl carrier protein (ACP) family.
       0.496
Acel_0209
KEGG: nfa:nfa4030 hypothetical protein.
  
     0.495
Acel_1165
PFAM: peptidase M20; peptidase dimerisation domain protein; KEGG: sco:SCO1676 hypothetical protein.
 
     0.493
Acel_0933
PFAM: Abortive infection protein; KEGG: sma:SAV6992 hypothetical protein.
  
     0.467
Your Current Organism:
Acidothermus cellulolyticus
NCBI taxonomy Id: 351607
Other names: A. cellulolyticus 11B, Acidothermus cellulolyticus 11B, Acidothermus cellulolyticus str. 11B, Acidothermus cellulolyticus strain 11B
Server load: low (8%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.