Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Acel_1027PFAM: DivIVA family protein; KEGG: tfu:Tfu_1118 hypothetical protein. (302 aa)    
Predicted Functional Partners:
Acel_1026
KEGG: tfu:Tfu_1117 hypothetical protein.
  
    0.804
Acel_2135
PFAM: glycosyl transferase, family 51; penicillin-binding protein, transpeptidase; KEGG: tfu:Tfu_0570 similar to membrane carboxypeptidase (penicillin-binding protein).
   
 
 0.730
sepF
Protein of unknown function DUF552; Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA.
  
  
 0.728
Acel_1014
Protein of unknown function UPF0001; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis; Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
  
  
 0.683
Acel_2004
PFAM: glycosyl transferase, family 51; penicillin-binding protein, transpeptidase; PASTA domain containing protein; KEGG: tfu:Tfu_0109 PASTA.
   
 
 0.640
ftsZ
Cell division protein FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
  
  
 0.631
Acel_1004
Peptidoglycan synthetase FtsI; PFAM: penicillin-binding protein, transpeptidase; Penicillin-binding protein, dimerisation domain; KEGG: fra:Francci3_1409 peptidoglycan glycosyltransferase.
     
 0.590
Acel_1009
Cell division-specific peptidoglycan biosynthesis regulator FtsW; TIGRFAM: cell division protein FtsW; PFAM: cell cycle protein; KEGG: fra:Francci3_1414 cell cycle protein; Belongs to the SEDS family.
     
 0.584
Acel_0019
PFAM: protein kinase; PASTA domain containing protein; SMART: tyrosine protein kinase; serine/threonine protein kinase; KEGG: tfu:Tfu_3066 tyrosine protein kinase:serine/threonine protein kinase:PASTA.
  
 
 0.571
Acel_0986
PFAM: protein of unknown function RIO1; protein kinase; PASTA domain containing protein; SMART: tyrosine protein kinase; serine/threonine protein kinase; KEGG: sma:SAV6092 putative eukaryotic-type serine/threonine protein kinase.
  
 
 0.571
Your Current Organism:
Acidothermus cellulolyticus
NCBI taxonomy Id: 351607
Other names: A. cellulolyticus 11B, Acidothermus cellulolyticus 11B, Acidothermus cellulolyticus str. 11B, Acidothermus cellulolyticus strain 11B
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