STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Acel_1041PFAM: Cupin 2, conserved barrel domain protein. (311 aa)    
Predicted Functional Partners:
Acel_1043
PFAM: peptidase M24; KEGG: hma:rrnB0212 aminopeptidase.
 
    0.893
Acel_1042
PFAM: amidohydrolase; Amidohydrolase 3; KEGG: reu:Reut_C6231 hypothetical protein.
 
     0.841
Acel_1040
PFAM: short-chain dehydrogenase/reductase SDR; KEGG: mlo:mlr2047 short chain dehydrogenase.
 
  
 0.832
Acel_1044
Transcriptional regulator, XRE family with cupin sensor; PFAM: helix-turn-helix domain protein; Cupin 2, conserved barrel domain protein; KEGG: sil:SPO0423 DNA-binding protein, putative.
  
  
 0.792
Acel_1231
Nucleotidyltransferase; PFAM: transferase hexapeptide repeat containing protein; Nucleotidyl transferase; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain II; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain III; KEGG: tfu:Tfu_1394 mannose-1-phosphate guanylyltransferase.
  
  
 0.530
sigA
RNA polymerase, sigma 70 subunit, RpoD; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.
   
 
 0.443
Acel_1713
RNA polymerase, sigma 28 subunit; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
   
 
 0.443
Acel_1039
PFAM: oxidoreductase domain protein.
  
    0.438
Acel_0894
KEGG: dsy:DSY0977 hypothetical protein.
 
     0.423
guaA
GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP.
     
 0.416
Your Current Organism:
Acidothermus cellulolyticus
NCBI taxonomy Id: 351607
Other names: A. cellulolyticus 11B, Acidothermus cellulolyticus 11B, Acidothermus cellulolyticus str. 11B, Acidothermus cellulolyticus strain 11B
Server load: low (10%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.