Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Acel_1068PFAM: AMP-dependent synthetase and ligase; KEGG: sru:SRU_1684 acetyl-CoA synthase. (713 aa)    
Predicted Functional Partners:
Acel_0284
PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; KEGG: tfu:Tfu_2674 2-oxoglutarate ferredoxin oxidoreductase, alpha subunit.
  
 
 0.937
Acel_0115
PFAM: Citrate synthase; KEGG: sco:SCO4388 citrate synthase; Belongs to the citrate synthase family.
  
 0.925
Acel_1658
KEGG: mbo:Mb1162 citrate synthase; TIGRFAM: 2-methylcitrate synthase/citrate synthase II; PFAM: Citrate synthase; Belongs to the citrate synthase family.
  
 0.925
Acel_0672
KEGG: tfu:Tfu_2394 acetyl-CoA acetyltransferase; TIGRFAM: acetyl-CoA acetyltransferases; PFAM: Thiolase; Belongs to the thiolase-like superfamily. Thiolase family.
  
 
 0.922
Acel_0874
Propionyl-CoA carboxylase; PFAM: carboxyl transferase; KEGG: fra:Francci3_3485 propionyl-CoA carboxylase.
  
 0.915
Acel_0548
PFAM: phosphoribosylglycinamide synthetase; Carbamoyl-phosphate synthase L chain, ATP-binding; Carbamoyl-phosphate synthetase large chain domain protein; biotin carboxylase domain protein; KEGG: gka:GK1599 acetyl-CoA carboxylase.
  
 0.912
Acel_0549
PFAM: biotin/lipoyl attachment domain-containing protein; KEGG: fra:Francci3_3765 biotin/lipoyl attachment.
  
 0.912
Acel_0701
Pyruvate ferredoxin oxidoreductase, alpha subunit; PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; KEGG: rfr:Rfer_2186 pyruvate flavodoxin/ferredoxin oxidoreductase-like.
  
 
 0.909
Acel_1799
TIGRFAM: methylmalonate-semialdehyde dehydrogenase; PFAM: aldehyde dehydrogenase; KEGG: tfu:Tfu_0687 methylmalonate-semialdehyde dehydrogenase.
   
  0.908
acsA
Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.
  
  
 
0.908
Your Current Organism:
Acidothermus cellulolyticus
NCBI taxonomy Id: 351607
Other names: A. cellulolyticus 11B, Acidothermus cellulolyticus 11B, Acidothermus cellulolyticus str. 11B, Acidothermus cellulolyticus strain 11B
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