Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-expression
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[Homology]
Score
Acel_1173PFAM: protein of unknown function DUF75; KEGG: fra:Francci3_2640 protein of unknown function DUF75. (283 aa)    
Predicted Functional Partners:
Acel_1174
Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
     
 0.717
Acel_0029
PFAM: FAD dependent oxidoreductase; KEGG: sco:SCO1661 putative glycerol-3-phosphate dehydrogenase.
      0.643
Acel_1175
TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 3; PFAM: Haloacid dehalogenase domain protein hydrolase; KEGG: tfu:Tfu_1824 hAD-superfamily hydrolase subfamily IA, variant 3:HAD-superfamily hydrolase, subfamily IA, variant 1.
 
     0.633
rpoZ
DNA-directed RNA polymerase subunit omega; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
 
     0.562
Acel_1225
Transcriptional regulator, MerR family; PFAM: regulatory protein, MerR; KEGG: sma:SAV6982 hypothetical protein.
  
     0.467
Acel_0288
KEGG: sco:SCO4636 hypothetical protein; Belongs to the UPF0336 family.
  
     0.465
Acel_1133
PFAM: cytochrome oxidase assembly; KEGG: sma:SAV6320 putative integral membrane transport protein.
  
     0.438
Acel_0963
Menaquinol-cytochrome c reductase cytochrome c1 subunit precursor; PFAM: cytochrome c, class I; KEGG: sco:SCO2150 cytochrome C heme-binding subunit.
  
     0.427
Acel_0021
Cell elongation-specific peptidoglycan biosynthesis regulator RodA; PFAM: cell cycle protein; KEGG: nfa:nfa830 putative cell division protein; Belongs to the SEDS family.
  
     0.422
Acel_1380
PFAM: Chlorite dismutase; KEGG: tfu:Tfu_1896 hypothetical protein.
  
     0.421
Your Current Organism:
Acidothermus cellulolyticus
NCBI taxonomy Id: 351607
Other names: A. cellulolyticus 11B, Acidothermus cellulolyticus 11B, Acidothermus cellulolyticus str. 11B, Acidothermus cellulolyticus strain 11B
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