Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Acel_1180KEGG: sma:SAV6672 putative RecB family exonuclease. (266 aa)    
Predicted Functional Partners:
Acel_1352
KEGG: sma:SAV6829 secreted protein.
  
     0.645
Acel_1181
Peptidase M50; PFAM: CBS domain containing protein; peptidase M50; KEGG: sco:SCO1652 hypothetical protein; Belongs to the peptidase M50B family.
       0.618
Acel_2137
PFAM: transcriptional regulator PadR family protein; KEGG: sco:SCO3900 hypothetical protein.
  
     0.598
Acel_1353
Phosphatidylinositol alpha-mannosyltransferase; PFAM: glycosyl transferase, group 1; KEGG: tfu:Tfu_2101 phosphatidyl-myo-inositol alpha-mannosyltransferase.
  
     0.593
Acel_1182
tRNA (adenine-58-N(1)-) methyltransferase; Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA.
       0.582
Acel_1354
PFAM: lipid A biosynthesis acyltransferase; KEGG: tfu:Tfu_2102 lipid A biosynthesis lauroyl acyltransferase.
  
     0.563
Acel_2070
KEGG: cjk:jk0371 hypothetical protein.
  
     0.535
pafA
Protein of unknown function DUF245 domain protein; Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side- chain amino group of a substrate lysine.
 
   
 0.502
Acel_0375
TIGRFAM: ATP-dependent DNA helicase PcrA; PFAM: UvrD/REP helicase; KEGG: sco:SCO4797 putative ATP-dependent DNA helicase II.
  
   0.485
Acel_1178
PFAM: protein of unknown function DUF214; KEGG: fra:Francci3_2636 protein of unknown function DUF214.
       0.478
Your Current Organism:
Acidothermus cellulolyticus
NCBI taxonomy Id: 351607
Other names: A. cellulolyticus 11B, Acidothermus cellulolyticus 11B, Acidothermus cellulolyticus str. 11B, Acidothermus cellulolyticus strain 11B
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