STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Acel_1224PFAM: protein of unknown function DUF151; KEGG: sco:SCO1382 hypothetical protein. (162 aa)    
Predicted Functional Partners:
Acel_1223
Transcriptional regulator, MerR family; SMART: regulatory protein, MerR; KEGG: mpa:MAP1543 hypothetical protein.
     
 0.788
Acel_1225
Transcriptional regulator, MerR family; PFAM: regulatory protein, MerR; KEGG: sma:SAV6982 hypothetical protein.
 
   
 0.694
Acel_1226
FHA domain containing protein; PFAM: Forkhead-associated protein; KEGG: fra:Francci3_1468 FHA domain containing protein.
 
   
 0.656
Acel_1228
PFAM: protein of unknown function DUF881; KEGG: mpa:MAP1538 hypothetical protein.
     
 0.623
arc
Vesicle-fusing ATPase; ATPase which is responsible for recognizing, binding, unfolding and translocation of pupylated proteins into the bacterial 20S proteasome core particle. May be essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase may function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis.
  
    0.598
Acel_1230
PFAM: protein of unknown function DUF881; KEGG: sco:SCO1387 membrane associated protein.
     
 0.588
Acel_1232
PFAM: CDP-alcohol phosphatidyltransferase; KEGG: tfu:Tfu_1393 putative CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyl-transferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
 
     0.524
gcvH
Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
       0.506
gcvP
Glycine dehydrogenase (decarboxylating); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family.
       0.493
Acel_1229
PFAM: protein of unknown function DUF1290; KEGG: sco:SCO1386 integral membrane protein.
       0.446
Your Current Organism:
Acidothermus cellulolyticus
NCBI taxonomy Id: 351607
Other names: A. cellulolyticus 11B, Acidothermus cellulolyticus 11B, Acidothermus cellulolyticus str. 11B, Acidothermus cellulolyticus strain 11B
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