STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Acel_1250TIGRFAM: HAD-superfamily hydrolase, subfamily IIA; PFAM: Haloacid dehalogenase domain protein hydrolase; KEGG: tfu:Tfu_2038 HAD-superfamily hydrolase, subfamily IIA. (338 aa)    
Predicted Functional Partners:
Acel_1253
PFAM: Tetratricopeptide TPR_4; KEGG: tfu:Tfu_2042 hypothetical protein.
  
 
 0.947
Acel_1251
PFAM: Tetratricopeptide TPR_2 repeat protein; KEGG: fra:Francci3_3164 hypothetical protein.
   
 
 0.825
Acel_1333
Recombination protein MgsA; PFAM: magnesium chelatase, ChlI subunit; AAA ATPase, central domain protein; ATPase associated with various cellular activities, AAA_5; SMART: AAA ATPase; KEGG: sma:SAV6846 putative ATP/GTP-binding protein.
 
      0.665
Acel_1252
PFAM: Uncharacterised conserved protein UCP033563; KEGG: fra:Francci3_3165 uncharacterised conserved protein UCP033563.
       0.643
Acel_1245
DNA replication and repair protein RecN; May be involved in recombinational repair of damaged DNA.
    
 0.574
infB
Bacterial translation initiation factor 2 (bIF-2); One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
 
    0.539
nadK
NAD(+) kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
     
 0.482
cmk
Cytidylate kinase; KEGG: nfa:nfa20120 putative cytidylate kinase; TIGRFAM: cytidylate kinase; PFAM: cytidylate kinase region.
  
    0.447
lspA
Signal peptidase II; This protein specifically catalyzes the removal of signal peptides from prolipoproteins; Belongs to the peptidase A8 family.
 
    0.432
Your Current Organism:
Acidothermus cellulolyticus
NCBI taxonomy Id: 351607
Other names: A. cellulolyticus 11B, Acidothermus cellulolyticus 11B, Acidothermus cellulolyticus str. 11B, Acidothermus cellulolyticus strain 11B
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.