| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Acel_0387 | Acel_2128 | Acel_0387 | Acel_2128 | Malate dehydrogenase (NAD); Catalyzes the reversible oxidation of malate to oxaloacetate. | KEGG: sma:SAV7077 putative adenylosuccinate lyase; TIGRFAM: adenylosuccinate lyase; PFAM: fumarate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | 0.846 |
| Acel_0387 | argH | Acel_0387 | Acel_1256 | Malate dehydrogenase (NAD); Catalyzes the reversible oxidation of malate to oxaloacetate. | TIGRFAM: argininosuccinate lyase; PFAM: fumarate lyase; KEGG: fra:Francci3_3168 argininosuccinate lyase. | 0.833 |
| Acel_0387 | argR | Acel_0387 | Acel_1258 | Malate dehydrogenase (NAD); Catalyzes the reversible oxidation of malate to oxaloacetate. | Transcriptional regulator, ArgR family; Regulates arginine biosynthesis genes. | 0.427 |
| Acel_0387 | fumC | Acel_0387 | Acel_1879 | Malate dehydrogenase (NAD); Catalyzes the reversible oxidation of malate to oxaloacetate. | Fumarase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. | 0.982 |
| Acel_2128 | Acel_0387 | Acel_2128 | Acel_0387 | KEGG: sma:SAV7077 putative adenylosuccinate lyase; TIGRFAM: adenylosuccinate lyase; PFAM: fumarate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | Malate dehydrogenase (NAD); Catalyzes the reversible oxidation of malate to oxaloacetate. | 0.846 |
| Acel_2128 | argH | Acel_2128 | Acel_1256 | KEGG: sma:SAV7077 putative adenylosuccinate lyase; TIGRFAM: adenylosuccinate lyase; PFAM: fumarate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | TIGRFAM: argininosuccinate lyase; PFAM: fumarate lyase; KEGG: fra:Francci3_3168 argininosuccinate lyase. | 0.913 |
| argB | argC | Acel_1261 | Acel_1263 | N-acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily. | N-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. | 0.999 |
| argB | argD | Acel_1261 | Acel_1260 | N-acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily. | TIGRFAM: acetylornithine and succinylornithine aminotransferases; PFAM: aminotransferase class-III; KEGG: tfu:Tfu_2054 acetylornithine and succinylornithine aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily. | 0.993 |
| argB | argF | Acel_1261 | Acel_1259 | N-acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily. | Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family. | 0.992 |
| argB | argG | Acel_1261 | Acel_1257 | N-acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily. | PFAM: argininosuccinate synthase; KEGG: tfu:Tfu_2052 argininosuccinate synthase; Belongs to the argininosuccinate synthase family. Type 1 subfamily. | 0.989 |
| argB | argH | Acel_1261 | Acel_1256 | N-acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily. | TIGRFAM: argininosuccinate lyase; PFAM: fumarate lyase; KEGG: fra:Francci3_3168 argininosuccinate lyase. | 0.990 |
| argB | argJ | Acel_1261 | Acel_1262 | N-acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily. | Glutamate N-acetyltransferase; Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate. Belongs to the ArgJ family. | 0.999 |
| argB | argR | Acel_1261 | Acel_1258 | N-acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily. | Transcriptional regulator, ArgR family; Regulates arginine biosynthesis genes. | 0.995 |
| argC | argB | Acel_1263 | Acel_1261 | N-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. | N-acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily. | 0.999 |
| argC | argD | Acel_1263 | Acel_1260 | N-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. | TIGRFAM: acetylornithine and succinylornithine aminotransferases; PFAM: aminotransferase class-III; KEGG: tfu:Tfu_2054 acetylornithine and succinylornithine aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily. | 0.996 |
| argC | argF | Acel_1263 | Acel_1259 | N-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. | Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family. | 0.983 |
| argC | argG | Acel_1263 | Acel_1257 | N-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. | PFAM: argininosuccinate synthase; KEGG: tfu:Tfu_2052 argininosuccinate synthase; Belongs to the argininosuccinate synthase family. Type 1 subfamily. | 0.983 |
| argC | argH | Acel_1263 | Acel_1256 | N-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. | TIGRFAM: argininosuccinate lyase; PFAM: fumarate lyase; KEGG: fra:Francci3_3168 argininosuccinate lyase. | 0.984 |
| argC | argJ | Acel_1263 | Acel_1262 | N-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. | Glutamate N-acetyltransferase; Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate. Belongs to the ArgJ family. | 0.997 |
| argC | argR | Acel_1263 | Acel_1258 | N-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. | Transcriptional regulator, ArgR family; Regulates arginine biosynthesis genes. | 0.923 |