Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Acel_1401KEGG: sma:SAV2398 hypothetical protein. (229 aa)    
Predicted Functional Partners:
dut
Deoxyuridine 5'-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family.
       0.817
Acel_1404
KEGG: tfu:Tfu_1939 hypothetical protein.
 
     0.807
rbpA
Conserved hypothetical protein; Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters.
  
     0.715
Acel_0949
KEGG: sco:SCO2169 integral membrane protein.
  
     0.702
rpoZ
DNA-directed RNA polymerase subunit omega; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
  
     0.694
Acel_1026
KEGG: tfu:Tfu_1117 hypothetical protein.
  
     0.686
Acel_1223
Transcriptional regulator, MerR family; SMART: regulatory protein, MerR; KEGG: mpa:MAP1543 hypothetical protein.
  
     0.665
Acel_1400
PFAM: nucleic acid binding, OB-fold, tRNA/helicase-type; KEGG: sma:SAV2394 hypothetical protein.
       0.656
Acel_1880
KEGG: tfu:Tfu_0458 secreted protein.
  
     0.627
Acel_1403
KEGG: pac:PPA1053 hypothetical protein.
       0.605
Your Current Organism:
Acidothermus cellulolyticus
NCBI taxonomy Id: 351607
Other names: A. cellulolyticus 11B, Acidothermus cellulolyticus 11B, Acidothermus cellulolyticus str. 11B, Acidothermus cellulolyticus strain 11B
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