STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Acel_1425PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent enzymes; aminotransferase class-III; KEGG: sco:SCO3920 putative cystathionine/methionine gamma-synthase/lyase. (400 aa)    
Predicted Functional Partners:
Acel_1174
Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
  
 
 0.983
metE
Methionine synthase (B12-independent); Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family.
  
 
 0.957
Acel_0059
Thiosulfate sulfurtransferase; PFAM: Rhodanese domain protein; KEGG: tfu:Tfu_2719 thiosulfate sulfurtransferase.
 
 
 0.941
Acel_1417
Thiosulfate sulfurtransferase; PFAM: Rhodanese domain protein; KEGG: sco:SCO5854 thiosulfate sulfurtransferase.
  
 
 0.935
Acel_0711
KEGG: sco:SCO5523 branched-chain amino acid aminotransferase; TIGRFAM: branched-chain amino acid aminotransferase; PFAM: aminotransferase, class IV.
   
 0.923
Acel_0292
L-aspartate aminotransferase apoenzyme; PFAM: aminotransferase, class I and II; KEGG: sco:SCO4645 aspartate aminotransferase.
  
 
 0.922
Acel_1687
TIGRFAM: cysteine synthases; PFAM: Pyridoxal-5'-phosphate-dependent enzyme, beta subunit; KEGG: fra:Francci3_0868 cysteine synthases.
 
 0.918
metG
methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
   
 
 0.912
Acel_2148
TIGRFAM: thioredoxin reductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: fra:Francci3_4536 thioredoxin reductase.
   
 
 0.907
ahcY
Adenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.
 
 0.889
Your Current Organism:
Acidothermus cellulolyticus
NCBI taxonomy Id: 351607
Other names: A. cellulolyticus 11B, Acidothermus cellulolyticus 11B, Acidothermus cellulolyticus str. 11B, Acidothermus cellulolyticus strain 11B
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