STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Acel_1434Diguanylate cyclase/phosphodiesterase with GAF sensor; TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; EAL domain protein; GAF domain protein; KEGG: ava:Ava_2710 putative diguanylate cyclase/phosphodiesterase (GGDEF & EAL domains) with PAS/PAC sensor(s). (746 aa)    
Predicted Functional Partners:
Acel_1566
TIGRFAM: ammonium transporter; PFAM: Rh family protein/ammonium transporter; KEGG: fra:Francci3_0422 ammonium transporter.
 
      0.808
Acel_1612
TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; KEGG: dar:Daro_3975 GGDEF.
  
   0.782
Acel_2100
KEGG: pfl:PFL_3824 sensory box histidine kinase/response regulator; TIGRFAM: PAS sensor protein; PFAM: response regulator receiver; ATP-binding region, ATPase domain protein domain protein; histidine kinase A domain protein domain protein; PAS fold-3 domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein.
 
 0.778
Acel_1420
TIGRFAM: PAS sensor protein; diguanylate cyclase; PFAM: GGDEF domain containing protein; EAL domain protein; PAS fold-3 domain protein; KEGG: bja:bll0955 hypothetical protein.
 
 
0.687
Acel_1740
TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; EAL domain protein; KEGG: mag:amb2277 predicted signal transduction protein containing a membrane domain.
 
 
0.550
Acel_1433
PFAM: HhH-GPD family protein; KEGG: sma:SAV4172 hypothetical protein.
       0.546
Acel_2099
PFAM: EAL domain protein; response regulator receiver; KEGG: tbd:Tbd_1061 putative diguanylate phosphodiesterase (EAL domain) with GAF sensor.
  
0.531
Acel_0546
PFAM: metal-dependent phosphohydrolase, HD sub domain; SMART: metal-dependent phosphohydrolase, HD region; KEGG: sco:SCO5218 integral membrane protein.
   
 0.512
Acel_0165
Diguanylate cyclase with GAF sensor; TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; GAF domain protein; histidine kinase, HAMP region domain protein; KEGG: ade:Adeh_2704 diguanylate cyclase (GGDEF domain).
 
 
0.506
Acel_1788
PFAM: MCP methyltransferase, CheR-type; KEGG: rpc:RPC_3801 MCP methyltransferase, CheR-type.
 
      0.493
Your Current Organism:
Acidothermus cellulolyticus
NCBI taxonomy Id: 351607
Other names: A. cellulolyticus 11B, Acidothermus cellulolyticus 11B, Acidothermus cellulolyticus str. 11B, Acidothermus cellulolyticus strain 11B
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