Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Acel_1446Cysteine--tRNA ligase; PFAM: cysteinyl-tRNA synthetase, class Ia; KEGG: fra:Francci3_2642 cysteine--tRNA ligase. (373 aa)    
Predicted Functional Partners:
cysS
KEGG: tfu:Tfu_0212 cysteinyl-tRNA synthetase, class Ia; TIGRFAM: cysteinyl-tRNA synthetase; PFAM: cysteinyl-tRNA synthetase, class Ia; Belongs to the class-I aminoacyl-tRNA synthetase family.
  
  
 
0.916
Acel_1687
TIGRFAM: cysteine synthases; PFAM: Pyridoxal-5'-phosphate-dependent enzyme, beta subunit; KEGG: fra:Francci3_0868 cysteine synthases.
  
 
 0.904
serS
seryl-tRNA synthetase; Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further converted into selenocysteinyl- tRNA(Sec).
 
 
 0.711
Acel_1940
KEGG: pab:PAB0773 putative acetyltransferase.
  
  
 0.612
pheT
TIGRFAM: phenylalanyl-tRNA synthetase, beta subunit; KEGG: sma:SAV6743 putative phenylalanyl-tRNA synthetase beta subunit; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
  
  
 0.579
Acel_1931
PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: mba:Mbar_A3370 ABC transporter, ATP-binding protein.
  
     0.546
Acel_1447
KEGG: fra:Francci3_0974 hypothetical protein.
       0.459
Acel_1448
Periplasmic sensor signal transduction histidine kinase; PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase, HAMP region domain protein; histidine kinase A domain protein domain protein; KEGG: fra:Francci3_0235 periplasmic sensor signal transduction histidine kinase.
       0.440
leuS
TIGRFAM: leucyl-tRNA synthetase; KEGG: tfu:Tfu_2156 leucyl-tRNA synthetase bacterial/mitochondrial, class Ia; Belongs to the class-I aminoacyl-tRNA synthetase family.
  
 
 0.430
Acel_1449
Two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: fra:Francci3_0234 two component transcriptional regulator, winged helix family.
       0.418
Your Current Organism:
Acidothermus cellulolyticus
NCBI taxonomy Id: 351607
Other names: A. cellulolyticus 11B, Acidothermus cellulolyticus 11B, Acidothermus cellulolyticus str. 11B, Acidothermus cellulolyticus strain 11B
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