Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
Acel_1448Periplasmic sensor signal transduction histidine kinase; PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase, HAMP region domain protein; histidine kinase A domain protein domain protein; KEGG: fra:Francci3_0235 periplasmic sensor signal transduction histidine kinase. (524 aa)    
Predicted Functional Partners:
Acel_1275
TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; response regulator receiver; KEGG: tte:TTE1717 response regulators consisting of a CheY-like receiver domain and a HTH DNA-binding domain.
 
 0.961
Acel_1449
Two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: fra:Francci3_0234 two component transcriptional regulator, winged helix family.
 
 0.960
Acel_1595
Two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: nfa:nfa49640 putative two-component system response regulator.
 
 0.902
Acel_1874
PFAM: response regulator receiver; KEGG: cyb:CYB_1937 response regulator.
 
 0.891
Acel_1832
Two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: nfa:nfa27150 putative two-component system response regulator.
 
 0.880
Acel_0088
Two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: tfu:Tfu_2910 response regulator receiver.
 
 0.876
Acel_1765
Two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: tfu:Tfu_2496 response regulator receiver.
 
 0.867
Acel_0627
PFAM: response regulator receiver; KEGG: sco:SCO5351 regulatory protein.
 
 0.851
Acel_1606
Two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: sma:SAV5250 two-component system response regulator.
 
 0.848
Acel_1196
Two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: sco:SCO5872 putative turgor pressure regulator.
 
 0.830
Your Current Organism:
Acidothermus cellulolyticus
NCBI taxonomy Id: 351607
Other names: A. cellulolyticus 11B, Acidothermus cellulolyticus 11B, Acidothermus cellulolyticus str. 11B, Acidothermus cellulolyticus strain 11B
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