Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Acel_1473PFAM: Alcohol dehydrogenase, zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KEGG: bja:blr6532 putative dehydrogenase. (340 aa)    
Predicted Functional Partners:
Acel_0138
PFAM: Alcohol dehydrogenase, zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KEGG: fra:Francci3_0264 alcohol dehydrogenase GroES-like.
 
 
 0.628
Acel_0429
PFAM: Alcohol dehydrogenase, zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KEGG: sma:SAV5771 alcohol dehydrogenase.
 
    
0.538
guaA
GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP.
    
  0.515
purH
KEGG: tfu:Tfu_2572 AICARFT/IMPCHase bienzyme; TIGRFAM: phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; PFAM: AICARFT/IMPCHase bienzyme; MGS domain protein.
    
  0.506
pgk
Phosphoglycerate kinase / triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family.
   
 
 0.429
Your Current Organism:
Acidothermus cellulolyticus
NCBI taxonomy Id: 351607
Other names: A. cellulolyticus 11B, Acidothermus cellulolyticus 11B, Acidothermus cellulolyticus str. 11B, Acidothermus cellulolyticus strain 11B
Server load: low (12%) [HD]