Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
rncRNAse III; Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism. (246 aa)    
Predicted Functional Partners:
rpmF
TIGRFAM: ribosomal protein L32; PFAM: ribosomal L32p protein; KEGG: nfa:nfa41850 putative ribosomal protein L32; Belongs to the bacterial ribosomal protein bL32 family.
  
  0.972
era
GTP-binding protein Era; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
 
  
 0.908
Acel_1796
PFAM: PHP C-terminal domain protein; SMART: phosphoesterase PHP domain protein; KEGG: sma:SAV3103 hypothetical protein.
      0.902
rplS
LSU ribosomal protein L19P; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.
 
 0.897
rpsO
SSU ribosomal protein S15P; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
  
 
 0.885
rpmA
PFAM: ribosomal protein L27; KEGG: tfu:Tfu_2181 ribosomal protein L27; Belongs to the bacterial ribosomal protein bL27 family.
  
 
 0.877
rplQ
PFAM: ribosomal protein L17; KEGG: sma:SAV4954 putative ribosomal protein L17.
   
 0.876
rpsP
PFAM: ribosomal protein S16; KEGG: fra:Francci3_3594 ribosomal protein S16; Belongs to the bacterial ribosomal protein bS16 family.
 
 
 0.876
rplO
LSU ribosomal protein L15P; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family.
   
 0.870
rpsI
PFAM: ribosomal protein S9; KEGG: tfu:Tfu_2613 30S ribosomal protein S9; Belongs to the universal ribosomal protein uS9 family.
   
 
 0.870
Your Current Organism:
Acidothermus cellulolyticus
NCBI taxonomy Id: 351607
Other names: A. cellulolyticus 11B, Acidothermus cellulolyticus 11B, Acidothermus cellulolyticus str. 11B, Acidothermus cellulolyticus strain 11B
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