STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
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[Homology]
Score
Acel_1692Putative nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. (443 aa)    
Predicted Functional Partners:
Acel_1717
PFAM: isochorismatase hydrolase; KEGG: pac:PPA0993 pyrazinamidase/nicotinamidase.
 
 0.997
Acel_0214
KEGG: sco:SCO3381 nicotinate-nucleotide pyrophophorylase; TIGRFAM: nicotinate-nucleotide pyrophosphorylase; PFAM: Quinolinate phosphoribosyl transferase; Belongs to the NadC/ModD family.
   
 0.978
nadD
Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
 
 0.972
Acel_1497
TIGRFAM: competence/damage-inducible protein CinA; PFAM: molybdopterin binding domain; CinA domain protein; KEGG: fra:Francci3_3538 competence-damaged protein; Belongs to the CinA family.
  
 
 0.959
Acel_0896
PFAM: ferredoxin; [2Fe-2S]-binding domain protein; KEGG: pae:PA1602 probable oxidoreductase.
     
  0.900
Acel_0897
PFAM: aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding; KEGG: bja:blr6047 putative oxidoreductase protein.
     
  0.900
Acel_2058
KEGG: tel:tll1801 similar to poly-gamma-glutamic synthesis PgsA protein.
  
    0.785
nadE
NH(3)-dependent NAD(+) synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
 
  
 0.765
clpS
ATP-dependent Clp protease adaptor protein ClpS; Involved in the modulation of the specificity of the ClpAP- mediated ATP-dependent protein degradation; Belongs to the ClpS family.
       0.652
Acel_1690
KEGG: tfu:Tfu_2371 hypothetical protein.
       0.643
Your Current Organism:
Acidothermus cellulolyticus
NCBI taxonomy Id: 351607
Other names: A. cellulolyticus 11B, Acidothermus cellulolyticus 11B, Acidothermus cellulolyticus str. 11B, Acidothermus cellulolyticus strain 11B
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