Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Acel_1697TIGRFAM: squalene/oxidosqualene cyclases; squalene-hopene cyclase; PFAM: Prenyltransferase/squalene oxidase; KEGG: fra:Francci3_0823 squalene cyclase. (633 aa)    
Predicted Functional Partners:
Acel_1699
PFAM: Radical SAM domain protein; KEGG: sco:SCO6766 hypothetical protein.
   
 0.987
Acel_1695
PFAM: amine oxidase; FAD dependent oxidoreductase; KEGG: sma:SAV1652 squalene/phytoene dehydrogenase.
 
   
 0.923
Acel_1694
PFAM: Squalene/phytoene synthase; KEGG: fra:Francci3_0820 squalene/phytoene synthase.
 
  
 0.900
Acel_1693
PFAM: Squalene/phytoene synthase; KEGG: fra:Francci3_0819 squalene/phytoene synthase.
 
  
 0.884
Acel_1696
PFAM: Polyprenyl synthetase; KEGG: fra:Francci3_0822 polyprenyl synthetase; Belongs to the FPP/GGPP synthase family.
 
  
 0.876
Acel_1698
Hypothetical protein; KEGG: fra:Francci3_0824 hydroxymethylbutenyl pyrophosphate reductase.
     
 0.786
Acel_1722
PFAM: glycosyl transferase, family 2; KEGG: fra:Francci3_0829 glycosyl transferase, family 2.
  
     0.764
Acel_1700
PFAM: protein of unknown function UPF0118; KEGG: fra:Francci3_1161 protein of unknown function UPF0118.
       0.555
dxs
1-deoxy-D-xylulose-5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily.
     
 0.434
Acel_1692
Putative nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family.
       0.421
Your Current Organism:
Acidothermus cellulolyticus
NCBI taxonomy Id: 351607
Other names: A. cellulolyticus 11B, Acidothermus cellulolyticus 11B, Acidothermus cellulolyticus str. 11B, Acidothermus cellulolyticus strain 11B
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