| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Acel_0235 | Acel_0236 | Acel_0235 | Acel_0236 | Porphobilinogen synthase; PFAM: delta-aminolevulinic acid dehydratase; KEGG: tfu:Tfu_2730 porphobilinogen synthase; Belongs to the ALAD family. | uroporphyrinogen-III synthase / uroporphyrinogen-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Uroporphyrinogen III synthase HEM4; KEGG: sma:SAV4741 uroporphyrin-III C-methyltransferase / uroporphyrinogen-III synthase. | 0.998 |
| Acel_0235 | Acel_0254 | Acel_0235 | Acel_0254 | Porphobilinogen synthase; PFAM: delta-aminolevulinic acid dehydratase; KEGG: tfu:Tfu_2730 porphobilinogen synthase; Belongs to the ALAD family. | PFAM: cytochrome c assembly protein; KEGG: fra:Francci3_0513 cytochrome c assembly protein. | 0.414 |
| Acel_0235 | Acel_1616 | Acel_0235 | Acel_1616 | Porphobilinogen synthase; PFAM: delta-aminolevulinic acid dehydratase; KEGG: tfu:Tfu_2730 porphobilinogen synthase; Belongs to the ALAD family. | TIGRFAM: uroporphyrin-III C-methyltransferase; siroheme synthase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: tfu:Tfu_2221 uroporphyrin-III C-methyltransferase, C-terminal:siroheme synthase, N-terminal. | 0.928 |
| Acel_0235 | Acel_1742 | Acel_0235 | Acel_1742 | Porphobilinogen synthase; PFAM: delta-aminolevulinic acid dehydratase; KEGG: tfu:Tfu_2730 porphobilinogen synthase; Belongs to the ALAD family. | PFAM: Uroporphyrinogen III synthase HEM4; KEGG: fra:Francci3_0793 uroporphyrinogen III synthase HEM4. | 0.664 |
| Acel_0235 | hemC | Acel_0235 | Acel_0237 | Porphobilinogen synthase; PFAM: delta-aminolevulinic acid dehydratase; KEGG: tfu:Tfu_2730 porphobilinogen synthase; Belongs to the ALAD family. | Hydroxymethylbilane synthase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | 0.998 |
| Acel_0235 | hemE | Acel_0235 | Acel_1382 | Porphobilinogen synthase; PFAM: delta-aminolevulinic acid dehydratase; KEGG: tfu:Tfu_2730 porphobilinogen synthase; Belongs to the ALAD family. | Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III. | 0.787 |
| Acel_0236 | Acel_0235 | Acel_0236 | Acel_0235 | uroporphyrinogen-III synthase / uroporphyrinogen-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Uroporphyrinogen III synthase HEM4; KEGG: sma:SAV4741 uroporphyrin-III C-methyltransferase / uroporphyrinogen-III synthase. | Porphobilinogen synthase; PFAM: delta-aminolevulinic acid dehydratase; KEGG: tfu:Tfu_2730 porphobilinogen synthase; Belongs to the ALAD family. | 0.998 |
| Acel_0236 | Acel_0254 | Acel_0236 | Acel_0254 | uroporphyrinogen-III synthase / uroporphyrinogen-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Uroporphyrinogen III synthase HEM4; KEGG: sma:SAV4741 uroporphyrin-III C-methyltransferase / uroporphyrinogen-III synthase. | PFAM: cytochrome c assembly protein; KEGG: fra:Francci3_0513 cytochrome c assembly protein. | 0.885 |
| Acel_0236 | Acel_1616 | Acel_0236 | Acel_1616 | uroporphyrinogen-III synthase / uroporphyrinogen-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Uroporphyrinogen III synthase HEM4; KEGG: sma:SAV4741 uroporphyrin-III C-methyltransferase / uroporphyrinogen-III synthase. | TIGRFAM: uroporphyrin-III C-methyltransferase; siroheme synthase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: tfu:Tfu_2221 uroporphyrin-III C-methyltransferase, C-terminal:siroheme synthase, N-terminal. | 0.988 |
| Acel_0236 | Acel_1742 | Acel_0236 | Acel_1742 | uroporphyrinogen-III synthase / uroporphyrinogen-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Uroporphyrinogen III synthase HEM4; KEGG: sma:SAV4741 uroporphyrin-III C-methyltransferase / uroporphyrinogen-III synthase. | PFAM: Uroporphyrinogen III synthase HEM4; KEGG: fra:Francci3_0793 uroporphyrinogen III synthase HEM4. | 0.914 |
| Acel_0236 | Acel_1743 | Acel_0236 | Acel_1743 | uroporphyrinogen-III synthase / uroporphyrinogen-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Uroporphyrinogen III synthase HEM4; KEGG: sma:SAV4741 uroporphyrin-III C-methyltransferase / uroporphyrinogen-III synthase. | TIGRFAM: nitrite reductase [NAD(P)H], small subunit; PFAM: Rieske [2Fe-2S] domain protein; KEGG: dge:Dgeo_2392 nitrite reductase (NAD(P)H) large subunit, NirD. | 0.682 |
| Acel_0236 | Acel_1744 | Acel_0236 | Acel_1744 | uroporphyrinogen-III synthase / uroporphyrinogen-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Uroporphyrinogen III synthase HEM4; KEGG: sma:SAV4741 uroporphyrin-III C-methyltransferase / uroporphyrinogen-III synthase. | TIGRFAM: nitrite reductase [NAD(P)H], large subunit; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; nitrite/sulfite reductase, hemoprotein beta-component, ferrodoxin domain protein; nitrite and sulphite reductase 4Fe-4S region; BFD domain protein [2Fe-2S]-binding domain protein; KEGG: fra:Francci3_0794 nitrite reductase (NAD(P)H) large subunit, NirB. | 0.512 |
| Acel_0236 | Acel_1745 | Acel_0236 | Acel_1745 | uroporphyrinogen-III synthase / uroporphyrinogen-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Uroporphyrinogen III synthase HEM4; KEGG: sma:SAV4741 uroporphyrin-III C-methyltransferase / uroporphyrinogen-III synthase. | PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; BFD domain protein [2Fe-2S]-binding domain protein; KEGG: nar:Saro_2968 nitrite reductase (NAD(P)H) large subunit, NirB. | 0.512 |
| Acel_0236 | hemC | Acel_0236 | Acel_0237 | uroporphyrinogen-III synthase / uroporphyrinogen-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Uroporphyrinogen III synthase HEM4; KEGG: sma:SAV4741 uroporphyrin-III C-methyltransferase / uroporphyrinogen-III synthase. | Hydroxymethylbilane synthase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | 0.999 |
| Acel_0236 | hemE | Acel_0236 | Acel_1382 | uroporphyrinogen-III synthase / uroporphyrinogen-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Uroporphyrinogen III synthase HEM4; KEGG: sma:SAV4741 uroporphyrin-III C-methyltransferase / uroporphyrinogen-III synthase. | Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III. | 0.960 |
| Acel_0254 | Acel_0235 | Acel_0254 | Acel_0235 | PFAM: cytochrome c assembly protein; KEGG: fra:Francci3_0513 cytochrome c assembly protein. | Porphobilinogen synthase; PFAM: delta-aminolevulinic acid dehydratase; KEGG: tfu:Tfu_2730 porphobilinogen synthase; Belongs to the ALAD family. | 0.414 |
| Acel_0254 | Acel_0236 | Acel_0254 | Acel_0236 | PFAM: cytochrome c assembly protein; KEGG: fra:Francci3_0513 cytochrome c assembly protein. | uroporphyrinogen-III synthase / uroporphyrinogen-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Uroporphyrinogen III synthase HEM4; KEGG: sma:SAV4741 uroporphyrin-III C-methyltransferase / uroporphyrinogen-III synthase. | 0.885 |
| Acel_0254 | Acel_1616 | Acel_0254 | Acel_1616 | PFAM: cytochrome c assembly protein; KEGG: fra:Francci3_0513 cytochrome c assembly protein. | TIGRFAM: uroporphyrin-III C-methyltransferase; siroheme synthase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: tfu:Tfu_2221 uroporphyrin-III C-methyltransferase, C-terminal:siroheme synthase, N-terminal. | 0.567 |
| Acel_0254 | Acel_1742 | Acel_0254 | Acel_1742 | PFAM: cytochrome c assembly protein; KEGG: fra:Francci3_0513 cytochrome c assembly protein. | PFAM: Uroporphyrinogen III synthase HEM4; KEGG: fra:Francci3_0793 uroporphyrinogen III synthase HEM4. | 0.554 |
| Acel_0254 | hemC | Acel_0254 | Acel_0237 | PFAM: cytochrome c assembly protein; KEGG: fra:Francci3_0513 cytochrome c assembly protein. | Hydroxymethylbilane synthase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | 0.476 |