STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Acel_1883PFAM: protein of unknown function DUF255; KEGG: tfu:Tfu_0451 conserved hypothetical protein. (658 aa)    
Predicted Functional Partners:
Acel_0614
Glycoside hydrolase, family 5; Has a very high specific activity on carboxymethylcellulose.
   
 
 0.999
Acel_0618
PFAM: cellulose-binding, family II; type 3a, cellulose-binding domain protein; glycosyl hydrolase, BNR repeat-containing protein; Fibronectin, type III domain protein; KEGG: tfu:Tfu_1612 cellulose-binding, family II, bacterial type.
  
 
 0.721
Acel_1884
methylated-DNA--protein-cysteine methyltransferase; Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
       0.653
mca
LmbE family protein; A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl-inositol) S- conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics; Belongs to the MshB deacetylase family. Mca subfamily.
       0.624
Acel_0173
KEGG: sma:SAV1698 hypothetical protein.
    
   0.620
Acel_1702
KEGG: sco:SCO6705 secreted protein.
    
   0.620
Acel_1924
KEGG: ret:RHE_CH01372 hypothetical protein.
    
   0.620
Acel_1926
Hypothetical protein; KEGG: fra:Francci3_1572 parallel beta-helix repeat protein.
    
   0.620
Acel_0767
PFAM: putative esterase; KEGG: fra:Francci3_2744 putative esterase.
    
   0.588
Acel_1885
Hypothetical protein.
       0.534
Your Current Organism:
Acidothermus cellulolyticus
NCBI taxonomy Id: 351607
Other names: A. cellulolyticus 11B, Acidothermus cellulolyticus 11B, Acidothermus cellulolyticus str. 11B, Acidothermus cellulolyticus strain 11B
Server load: low (28%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.