Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
Acel_1897Small-conductance mechanosensitive channel-like protein; KEGG: pto:PTO0513 mechanosensitive (MS) ion channel. (233 aa)    
Predicted Functional Partners:
gcvP
Glycine dehydrogenase (decarboxylating); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family.
   
    0.582
Acel_1896
PFAM: protein of unknown function DUF72; KEGG: sco:SCO1727 hypothetical protein.
       0.568
Acel_1895
KEGG: lxx:Lxx04330 hypothetical protein.
       0.531
msrA
Peptide methionine sulfoxide reductase; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.
     
 0.530
Acel_1892
KEGG: fra:Francci3_3905 magnesium chelatase, ChlI subunit.
       0.491
Acel_1893
PFAM: von Willebrand factor, type A; KEGG: fra:Francci3_3906 von Willebrand factor, type A.
       0.491
Acel_1894
PFAM: major facilitator superfamily MFS_1; KEGG: nfa:nfa44520 putative transporter.
       0.491
Your Current Organism:
Acidothermus cellulolyticus
NCBI taxonomy Id: 351607
Other names: A. cellulolyticus 11B, Acidothermus cellulolyticus 11B, Acidothermus cellulolyticus str. 11B, Acidothermus cellulolyticus strain 11B
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