Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
Acel_2044PFAM: NUDIX hydrolase; KEGG: mpa:MAP0346c hypothetical protein. (160 aa)    
Predicted Functional Partners:
Acel_2045
PFAM: Acetyl xylan esterase; KEGG: sma:SAV1302 putative cephalosporin C deacetylase.
       0.773
Acel_1376
PFAM: ATP dependent DNA ligase domain protein; ATP dependent DNA ligase; KEGG: sco:SCO6707 putative DNA ligase.
 
     0.494
Acel_1378
KEGG: sma:SAV1696 hypothetical protein.
  
     0.456
Acel_2046
Transcriptional regulator, LacI family; PFAM: regulatory protein, LacI; periplasmic binding protein/LacI transcriptional regulator; KEGG: tfu:Tfu_2790 regulatory protein, LacI.
       0.428
Your Current Organism:
Acidothermus cellulolyticus
NCBI taxonomy Id: 351607
Other names: A. cellulolyticus 11B, Acidothermus cellulolyticus 11B, Acidothermus cellulolyticus str. 11B, Acidothermus cellulolyticus strain 11B
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