STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Acel_2056PFAM: Na+/solute symporter; KEGG: sco:SCO5229 putative permease; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. (527 aa)    
Predicted Functional Partners:
Acel_0248
PFAM: Proline dehydrogenase; KEGG: tfu:Tfu_0434 proline dehydrogenase.
  
  
 0.831
Acel_1640
KEGG: bja:blr4464 probable ABC transporter ATP-binding/permease protein; TIGRFAM: polar amino acid ABC transporter, inner membrane subunit; PFAM: binding-protein-dependent transport systems inner membrane component; SMC domain protein; ABC transporter related; SMART: AAA ATPase; TC 3.A.1.3.-; 3.A.1.3.-.
  
  
 0.811
apt
Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
   
  
 0.608
pxpA
LamB/YcsF family protein; Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.
  
    0.540
Acel_2100
KEGG: pfl:PFL_3824 sensory box histidine kinase/response regulator; TIGRFAM: PAS sensor protein; PFAM: response regulator receiver; ATP-binding region, ATPase domain protein domain protein; histidine kinase A domain protein domain protein; PAS fold-3 domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein.
   
  
 0.509
Acel_0687
PFAM: short-chain dehydrogenase/reductase SDR; KEGG: sco:SCO1088 oxidoreductase.
  
    0.468
Acel_1068
PFAM: AMP-dependent synthetase and ligase; KEGG: sru:SRU_1684 acetyl-CoA synthase.
  
  
 0.433
Acel_1714
TIGRFAM: acetoacetyl-CoA synthase; PFAM: AMP-dependent synthetase and ligase; KEGG: bms:BR0021 acetoacetyl-CoA synthase.
  
  
 0.433
acsA
Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.
  
  
 0.433
Acel_0115
PFAM: Citrate synthase; KEGG: sco:SCO4388 citrate synthase; Belongs to the citrate synthase family.
   
  
 0.421
Your Current Organism:
Acidothermus cellulolyticus
NCBI taxonomy Id: 351607
Other names: A. cellulolyticus 11B, Acidothermus cellulolyticus 11B, Acidothermus cellulolyticus str. 11B, Acidothermus cellulolyticus strain 11B
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.