Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Acel_2085Zinc uptake regulator, Fur family; PFAM: ferric-uptake regulator; KEGG: sma:SAV5631 putative metal uptake regulation protein; Belongs to the Fur family. (138 aa)    
Predicted Functional Partners:
rpoA
DNA-directed RNA polymerase subunit alpha; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
 
 0.858
Acel_2087
PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: fra:Francci3_2478 ABC transporter related.
  
  
 0.824
Acel_2095
Ferric uptake regulator, Fur family; PFAM: ferric-uptake regulator; KEGG: nfa:nfa3250 putative ferric uptake regulator; Belongs to the Fur family.
  
   
 0.779
Acel_0061
Nickel uptake regulator, Fur family; PFAM: ferric-uptake regulator; KEGG: sco:SCO4180 iron uptake regulatory protein; Belongs to the Fur family.
  
     0.771
Acel_2086
PFAM: periplasmic solute binding protein; KEGG: fra:Francci3_2479 periplasmic solute binding protein.
  
  
 0.770
rpoB
DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
 
 0.731
Acel_2088
PFAM: ABC-3 protein; KEGG: fra:Francci3_2477 ABC-3.
  
  
 0.728
Acel_2089
PFAM: ABC-3 protein; KEGG: fra:Francci3_2476 ABC-3.
  
  
 0.728
rpoC
DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
   0.711
rpoZ
DNA-directed RNA polymerase subunit omega; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
   
   0.700
Your Current Organism:
Acidothermus cellulolyticus
NCBI taxonomy Id: 351607
Other names: A. cellulolyticus 11B, Acidothermus cellulolyticus 11B, Acidothermus cellulolyticus str. 11B, Acidothermus cellulolyticus strain 11B
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