Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Acel_2099PFAM: EAL domain protein; response regulator receiver; KEGG: tbd:Tbd_1061 putative diguanylate phosphodiesterase (EAL domain) with GAF sensor. (402 aa)    
Predicted Functional Partners:
Acel_2100
KEGG: pfl:PFL_3824 sensory box histidine kinase/response regulator; TIGRFAM: PAS sensor protein; PFAM: response regulator receiver; ATP-binding region, ATPase domain protein domain protein; histidine kinase A domain protein domain protein; PAS fold-3 domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein.
 
0.997
Acel_1420
TIGRFAM: PAS sensor protein; diguanylate cyclase; PFAM: GGDEF domain containing protein; EAL domain protein; PAS fold-3 domain protein; KEGG: bja:bll0955 hypothetical protein.
 
0.975
Acel_0546
PFAM: metal-dependent phosphohydrolase, HD sub domain; SMART: metal-dependent phosphohydrolase, HD region; KEGG: sco:SCO5218 integral membrane protein.
  
 0.942
Acel_1275
TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; response regulator receiver; KEGG: tte:TTE1717 response regulators consisting of a CheY-like receiver domain and a HTH DNA-binding domain.
 
 
0.942
Acel_0620
TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; KEGG: ade:Adeh_1576 diguanylate cyclase (GGDEF domain).
  
 0.915
Acel_1873
CheA signal transduction histidine kinase; PFAM: response regulator receiver; CheW domain protein; ATP-binding region, ATPase domain protein domain protein; Hpt domain protein; KEGG: ade:Adeh_0613 CheA signal transduction histidine kinase.
  
 
 0.906
Acel_0165
Diguanylate cyclase with GAF sensor; TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; GAF domain protein; histidine kinase, HAMP region domain protein; KEGG: ade:Adeh_2704 diguanylate cyclase (GGDEF domain).
  
 0.881
Acel_0932
TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; KEGG: nfa:nfa1410 hypothetical protein.
  
 0.841
Acel_1481
Diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s); KEGG: ana:all0219 hypothetical protein; TIGRFAM: PAS sensor protein; diguanylate cyclase; PFAM: GGDEF domain containing protein; EAL domain protein; PAS fold-3 domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein.
 
0.840
Acel_0089
Histidine kinase; PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase A domain protein domain protein; KEGG: sco:SCO4229 putative sensor kinase.
 
 0.833
Your Current Organism:
Acidothermus cellulolyticus
NCBI taxonomy Id: 351607
Other names: A. cellulolyticus 11B, Acidothermus cellulolyticus 11B, Acidothermus cellulolyticus str. 11B, Acidothermus cellulolyticus strain 11B
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