Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Acel_2106KEGG: sth:STH3328 hypothetical protein. (183 aa)    
Predicted Functional Partners:
Acel_2105
PFAM: prephenate dehydratase; amino acid-binding ACT domain protein; KEGG: fra:Francci3_2485 prephenate dehydratase.
  
    0.707
serS
seryl-tRNA synthetase; Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further converted into selenocysteinyl- tRNA(Sec).
       0.642
Acel_1238
Condensin subunit ScpA; Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves.
  
 
 0.630
Acel_2103
TIGRFAM: Cof-like hydrolase; HAD-superfamily hydrolase, subfamily IIB; PFAM: Haloacid dehalogenase domain protein hydrolase; sucrose-6F-phosphate phosphohydrolase; Haloacid dehalogenase domain protein hydrolase, type 3; KEGG: fra:Francci3_4318 Cof protein.
       0.610
Acel_0752
PFAM: cell cycle protein; KEGG: fra:Francci3_1215 cell cycle protein; Belongs to the SEDS family.
 
     0.441
Acel_2107
PFAM: PAS fold-4 domain protein.
       0.440
Acel_1389
PFAM: peptidase S8 and S53, subtilisin, kexin, sedolisin; KEGG: sma:SAV3319 subtilisin-like protease.
 
     0.433
gyrB
DNA gyrase subunit B; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
   
 
 0.419
Acel_1427
DNA topoisomerase IV subunit B; KEGG: tfu:Tfu_2134 DNA topoisomerase (ATP-hydrolyzing); PFAM: DNA gyrase, subunit B domain protein; ATP-binding region, ATPase domain protein domain protein; DNA topoisomerase, type IIA, subunit B, region 2 domain protein; SMART: DNA topoisomerase II.
   
 
 0.419
Acel_0749
Rod shape-determining protein MreC; Involved in formation and maintenance of cell shape.
 
    0.409
Your Current Organism:
Acidothermus cellulolyticus
NCBI taxonomy Id: 351607
Other names: A. cellulolyticus 11B, Acidothermus cellulolyticus 11B, Acidothermus cellulolyticus str. 11B, Acidothermus cellulolyticus strain 11B
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