STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Acel_2149TIGRFAM: thioredoxin; PFAM: Redoxin domain protein; Thioredoxin domain; KEGG: fra:Francci3_4537 thioredoxin; Belongs to the thioredoxin family. (108 aa)    
Predicted Functional Partners:
Acel_2148
TIGRFAM: thioredoxin reductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: fra:Francci3_4536 thioredoxin reductase.
 
 0.989
Acel_0866
PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: fra:Francci3_0530 FAD-dependent pyridine nucleotide-disulphide oxidoreductase.
  
 
 0.754
rho
Transcription termination factor Rho; Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA- dependent ATPase activity, and release of the mRNA from the DNA template.
 
  
 0.745
Acel_2146
RNA polymerase, sigma subunit, ECF family; PFAM: sigma-70 region 2 domain protein; sigma-70 region 4 domain protein; Sigma-70, region 4 type 2; KEGG: sco:SCO3892 putative RNA polymerase sigma factor; Belongs to the sigma-70 factor family. ECF subfamily.
     
 0.601
Acel_1794
PFAM: low molecular weight phosphotyrosine protein phosphatase; KEGG: nfa:nfa24510 putative arsenate reductase.
  
 
 0.595
Acel_2150
PFAM: Peptidoglycan-binding domain 1 protein; cell wall hydrolase/autolysin; KEGG: fra:Francci3_4538 cell wall hydrolase/autolysin.
   
   0.551
groS
Chaperonin Cpn10; Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter.
 
 
 0.542
groL1
Chaperonin GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.
   
 
 0.532
groL2
Chaperonin GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.
   
 
 0.532
dnaK
Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.
  
 
 0.524
Your Current Organism:
Acidothermus cellulolyticus
NCBI taxonomy Id: 351607
Other names: A. cellulolyticus 11B, Acidothermus cellulolyticus 11B, Acidothermus cellulolyticus str. 11B, Acidothermus cellulolyticus strain 11B
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.