STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Csac_0872PFAM: biotin/lipoyl attachment domain-containing protein; catalytic domain of components of various dehydrogenase complexes; E3 binding domain protein. (460 aa)    
Predicted Functional Partners:
Csac_0873
TIGRFAM: dihydrolipoamide dehydrogenase; PFAM: FAD-dependent pyridine nucleotide-disulfide oxidoreductase; pyridine nucleotide-disulfide oxidoreductase dimerisation region; HI0933 family protein.
 0.999
Csac_0874
PFAM: dehydrogenase, E1 component; Transketolase, central region; Transketolase domain protein.
 0.999
Csac_1503
PFAM: FAD-dependent pyridine nucleotide-disulfide oxidoreductase.
  
 0.973
Csac_2249
TIGRFAM: pyruvate/ketoisovalerate oxidoreductase, gamma subunit; PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein; pyruvate ferredoxin/flavodoxin oxidoreductase.
   
 0.947
Csac_2041
TIGRFAM: phosphate acetyltransferase; PFAM: phosphate acetyl/butaryl transferase.
  
 
 0.936
Csac_2248
PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; thiamine pyrophosphate enzyme domain protein TPP-binding.
   
 
 0.934
prs
Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
   
 0.918
Csac_1461
PFAM: thiamine pyrophosphate enzyme domain protein TPP-binding.
   
 
 0.908
Csac_1550
PFAM: thiamine pyrophosphate enzyme domain protein TPP-binding.
   
 
 0.908
Csac_1460
PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein.
     
 0.907
Your Current Organism:
Caldicellulosiruptor saccharolyticus
NCBI taxonomy Id: 351627
Other names: C. saccharolyticus DSM 8903, Caldicellulosiruptor saccharolyticus DSM 8903, Caldicellulosiruptor saccharolyticus str. DSM 8903, Caldicellulosiruptor saccharolyticus strain DSM 8903
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