STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Csac_1385SMART: AAA ATPase. (612 aa)    
Predicted Functional Partners:
Csac_1384
Hypothetical protein.
  
  
 0.832
Csac_1400
PFAM: TRAG family protein.
 
  
 0.801
Csac_2653
PFAM: TRAG family protein.
 
  
 0.799
Csac_1386
Hypothetical protein.
       0.736
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
  
  
 0.573
Csac_1454
Hypothetical protein.
 
   
 0.568
Csac_1387
Hypothetical protein.
       0.544
Csac_1383
Hypothetical protein.
       0.517
Csac_1378
PFAM: phage integrase family protein; Belongs to the 'phage' integrase family.
 
  
 0.485
Csac_1394
Hypothetical protein.
 
     0.437
Your Current Organism:
Caldicellulosiruptor saccharolyticus
NCBI taxonomy Id: 351627
Other names: C. saccharolyticus DSM 8903, Caldicellulosiruptor saccharolyticus DSM 8903, Caldicellulosiruptor saccharolyticus str. DSM 8903, Caldicellulosiruptor saccharolyticus strain DSM 8903
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.