node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Csac_0794 | Csac_1604 | Csac_0794 | Csac_1604 | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | TIGRFAM: malonyl CoA-acyl carrier protein transacylase; PFAM: acyl transferase domain protein. | 0.558 |
Csac_0794 | Csac_1652 | Csac_0794 | Csac_1652 | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Uroporphyrinogen III synthase HEM4; Belongs to the precorrin methyltransferase family. | 0.538 |
Csac_0794 | Csac_1653 | Csac_0794 | Csac_1653 | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | Porphobilinogen synthase; PFAM: delta-aminolevulinic acid dehydratase; Belongs to the ALAD family. | 0.615 |
Csac_0794 | hemC | Csac_0794 | Csac_1651 | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | 0.434 |
Csac_0794 | hemL | Csac_0794 | Csac_1654 | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | TIGRFAM: glutamate-1-semialdehyde-2,1-aminomutase; PFAM: aminotransferase class-III. | 0.513 |
Csac_0794 | hisI | Csac_0794 | Csac_2019 | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | PFAM: phosphoribosyl-AMP cyclohydrolase; phosphoribosyl-ATP pyrophosphohydrolase; In the N-terminal section; belongs to the PRA-CH family. | 0.432 |
Csac_0794 | ribA | Csac_0794 | Csac_0792 | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | GTP cyclohydrolase II; Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate; Belongs to the GTP cyclohydrolase II family. | 0.999 |
Csac_1604 | Csac_0794 | Csac_1604 | Csac_0794 | TIGRFAM: malonyl CoA-acyl carrier protein transacylase; PFAM: acyl transferase domain protein. | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.558 |
Csac_1604 | Csac_1653 | Csac_1604 | Csac_1653 | TIGRFAM: malonyl CoA-acyl carrier protein transacylase; PFAM: acyl transferase domain protein. | Porphobilinogen synthase; PFAM: delta-aminolevulinic acid dehydratase; Belongs to the ALAD family. | 0.778 |
Csac_1604 | hemL | Csac_1604 | Csac_1654 | TIGRFAM: malonyl CoA-acyl carrier protein transacylase; PFAM: acyl transferase domain protein. | TIGRFAM: glutamate-1-semialdehyde-2,1-aminomutase; PFAM: aminotransferase class-III. | 0.904 |
Csac_1650 | Csac_1652 | Csac_1650 | Csac_1652 | Siroheme synthase (precorrin-2 oxidase/ferrochelatase domain)-like protein. | TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Uroporphyrinogen III synthase HEM4; Belongs to the precorrin methyltransferase family. | 0.996 |
Csac_1650 | Csac_1653 | Csac_1650 | Csac_1653 | Siroheme synthase (precorrin-2 oxidase/ferrochelatase domain)-like protein. | Porphobilinogen synthase; PFAM: delta-aminolevulinic acid dehydratase; Belongs to the ALAD family. | 0.765 |
Csac_1650 | hemA | Csac_1650 | Csac_1649 | Siroheme synthase (precorrin-2 oxidase/ferrochelatase domain)-like protein. | Glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | 0.911 |
Csac_1650 | hemC | Csac_1650 | Csac_1651 | Siroheme synthase (precorrin-2 oxidase/ferrochelatase domain)-like protein. | Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | 0.874 |
Csac_1650 | hemL | Csac_1650 | Csac_1654 | Siroheme synthase (precorrin-2 oxidase/ferrochelatase domain)-like protein. | TIGRFAM: glutamate-1-semialdehyde-2,1-aminomutase; PFAM: aminotransferase class-III. | 0.761 |
Csac_1652 | Csac_0794 | Csac_1652 | Csac_0794 | TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Uroporphyrinogen III synthase HEM4; Belongs to the precorrin methyltransferase family. | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.538 |
Csac_1652 | Csac_1650 | Csac_1652 | Csac_1650 | TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Uroporphyrinogen III synthase HEM4; Belongs to the precorrin methyltransferase family. | Siroheme synthase (precorrin-2 oxidase/ferrochelatase domain)-like protein. | 0.996 |
Csac_1652 | Csac_1653 | Csac_1652 | Csac_1653 | TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Uroporphyrinogen III synthase HEM4; Belongs to the precorrin methyltransferase family. | Porphobilinogen synthase; PFAM: delta-aminolevulinic acid dehydratase; Belongs to the ALAD family. | 0.999 |
Csac_1652 | hemA | Csac_1652 | Csac_1649 | TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Uroporphyrinogen III synthase HEM4; Belongs to the precorrin methyltransferase family. | Glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | 0.980 |
Csac_1652 | hemC | Csac_1652 | Csac_1651 | TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Uroporphyrinogen III synthase HEM4; Belongs to the precorrin methyltransferase family. | Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | 0.999 |