STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
speESpermidine synthase; Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine. (278 aa)    
Predicted Functional Partners:
speH
Adenosylmethionine decarboxylase; Catalyzes the decarboxylation of S-adenosylmethionine to S- adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine; Belongs to the prokaryotic AdoMetDC family. Type 1 subfamily.
 
 0.999
Csac_1880
TIGRFAM: putative agmatinase; PFAM: Arginase/agmatinase/formiminoglutamase; Belongs to the arginase family.
 
 
 0.989
Csac_1361
PFAM: Orn/Lys/Arg decarboxylase, major region; aromatic amino acid beta-eliminating lyase/threonine aldolase; Orn/Lys/Arg decarboxylase domain protein.
  
 0.947
Csac_1924
Methylthioadenosine phosphorylase; Purine nucleoside phosphorylase involved in purine salvage.
  
 
 0.908
Csac_2325
Methylthioadenosine phosphorylase; Purine nucleoside phosphorylase involved in purine salvage.
  
 
 0.908
mtaD
Amidohydrolase; Catalyzes the deamination of 5-methylthioadenosine and S- adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine. Belongs to the metallo-dependent hydrolases superfamily. MTA/SAH deaminase family.
   
  0.907
Csac_1269
PFAM: surface presentation of antigens (SPOA) protein; flagellar motor switch protein FliM.
    
   0.729
Csac_1878
Hypothetical protein.
       0.561
Csac_1877
PFAM: glycosyl transferase, family 2.
  
    0.518
Csac_1881
PFAM: carboxyl transferase.
       0.443
Your Current Organism:
Caldicellulosiruptor saccharolyticus
NCBI taxonomy Id: 351627
Other names: C. saccharolyticus DSM 8903, Caldicellulosiruptor saccharolyticus DSM 8903, Caldicellulosiruptor saccharolyticus str. DSM 8903, Caldicellulosiruptor saccharolyticus strain DSM 8903
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