Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Csac_2012TIGRFAM: putative CoA-substrate-specific enzyme activase; PFAM: ATPase, BadF/BadG/BcrA/BcrD type. (331 aa)    
Predicted Functional Partners:
Csac_2014
Hypothetical protein.
     0.990
Csac_2013
Hypothetical protein.
   
 0.986
Csac_0829
Hypothetical protein.
     0.978
Csac_0832
Hypothetical protein.
   
 0.977
Csac_0380
PFAM: 2-hydroxyglutaryl-CoA dehydratase, D-component.
 
 
 0.776
Csac_0381
TIGRFAM: putative CoA-substrate-specific enzyme activase; PFAM: ATPase, BadF/BadG/BcrA/BcrD type; 2-hydroxyglutaryl-CoA dehydratase, D-component.
 
 
0.757
Csac_2015
DNA-(apurinic or apyrimidinic site) lyase; PFAM: helix-hairpin-helix motif; HhH-GPD family protein; SMART: iron-sulfur cluster loop.
       0.464
Csac_2011
PFAM: UBA/THIF-type NAD/FAD binding protein.
       0.431
miaA
tRNA delta(2)-isopentenylpyrophosphate transferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A); Belongs to the IPP transferase family.
 
      0.402
Your Current Organism:
Caldicellulosiruptor saccharolyticus
NCBI taxonomy Id: 351627
Other names: C. saccharolyticus DSM 8903, Caldicellulosiruptor saccharolyticus DSM 8903, Caldicellulosiruptor saccharolyticus str. DSM 8903, Caldicellulosiruptor saccharolyticus strain DSM 8903
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