Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Csac_2425Putative transcriptional regulator, CopG family. (81 aa)    
Predicted Functional Partners:
Csac_2424
PFAM: Radical SAM domain protein; biotin and thiamin synthesis associated.
 
     0.914
Csac_1123
TIGRFAM: small GTP-binding protein; PFAM: GTP-binding protein, HSR1-related; Miro domain protein.
 
    0.811
Csac_0491
PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB.
 
    0.744
Csac_0174
PFAM: transport system permease protein; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
  
 
 0.733
Csac_1049
PFAM: transport system permease protein; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
  
 
 0.733
Csac_1048
PFAM: periplasmic binding protein.
  
 
 0.701
Csac_1864
TIGRFAM: hydrogenase, Fe-only; PFAM: ferredoxin; 4Fe-4S ferredoxin, iron-sulfur binding domain protein; iron hydrogenase, small subunit; hydrogenase large subunit domain protein.
 
     0.471
Your Current Organism:
Caldicellulosiruptor saccharolyticus
NCBI taxonomy Id: 351627
Other names: C. saccharolyticus DSM 8903, Caldicellulosiruptor saccharolyticus DSM 8903, Caldicellulosiruptor saccharolyticus str. DSM 8903, Caldicellulosiruptor saccharolyticus strain DSM 8903
Server load: low (10%) [HD]