node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SFU26964.1 | SFU63487.1 | SAMN05421784_10185 | SAMN05421784_1167 | Anti sigma-E protein, RseA. | Hypothetical protein; Belongs to the UPF0250 family. | 0.486 |
SFU26964.1 | mutH | SAMN05421784_10185 | SAMN05421784_12014 | Anti sigma-E protein, RseA. | DNA mismatch repair protein MutH; Sequence-specific endonuclease that cleaves unmethylated GATC sequences. It is involved in DNA mismatch repair. Belongs to the MutH family. | 0.592 |
SFU26964.1 | proQ | SAMN05421784_10185 | SAMN05421784_11732 | Anti sigma-E protein, RseA. | ProP effector; RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities. May regulate ProP activity through an RNA-based, post-transcriptional mechanism. Belongs to the ProQ family. | 0.588 |
SFU26964.1 | rraB | SAMN05421784_10185 | SAMN05421784_11946 | Anti sigma-E protein, RseA. | Hypothetical protein; Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. | 0.645 |
SFU26964.1 | seqA | SAMN05421784_10185 | SAMN05421784_12833 | Anti sigma-E protein, RseA. | Negative regulator of replication initiation SeqA; Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated. | 0.678 |
SFU35716.1 | SFU63487.1 | SAMN05421784_10439 | SAMN05421784_1167 | Putative thioredoxin. | Hypothetical protein; Belongs to the UPF0250 family. | 0.455 |
SFU63487.1 | SFU26964.1 | SAMN05421784_1167 | SAMN05421784_10185 | Hypothetical protein; Belongs to the UPF0250 family. | Anti sigma-E protein, RseA. | 0.486 |
SFU63487.1 | SFU35716.1 | SAMN05421784_1167 | SAMN05421784_10439 | Hypothetical protein; Belongs to the UPF0250 family. | Putative thioredoxin. | 0.455 |
SFU63487.1 | SFU63504.1 | SAMN05421784_1167 | SAMN05421784_1168 | Hypothetical protein; Belongs to the UPF0250 family. | Penicillin-binding protein 6. Serine peptidase. MEROPS family S11; Belongs to the peptidase S11 family. | 0.561 |
SFU63487.1 | fadR | SAMN05421784_1167 | SAMN05421784_1574 | Hypothetical protein; Belongs to the UPF0250 family. | Transcriptional regulator, GntR family; Multifunctional regulator of fatty acid metabolism. | 0.471 |
SFU63487.1 | lptE | SAMN05421784_1167 | SAMN05421784_11616 | Hypothetical protein; Belongs to the UPF0250 family. | LPS-assembly lipoprotein; Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane. | 0.537 |
SFU63487.1 | mutH | SAMN05421784_1167 | SAMN05421784_12014 | Hypothetical protein; Belongs to the UPF0250 family. | DNA mismatch repair protein MutH; Sequence-specific endonuclease that cleaves unmethylated GATC sequences. It is involved in DNA mismatch repair. Belongs to the MutH family. | 0.509 |
SFU63487.1 | proQ | SAMN05421784_1167 | SAMN05421784_11732 | Hypothetical protein; Belongs to the UPF0250 family. | ProP effector; RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities. May regulate ProP activity through an RNA-based, post-transcriptional mechanism. Belongs to the ProQ family. | 0.501 |
SFU63487.1 | rraB | SAMN05421784_1167 | SAMN05421784_11946 | Hypothetical protein; Belongs to the UPF0250 family. | Hypothetical protein; Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. | 0.539 |
SFU63487.1 | seqA | SAMN05421784_1167 | SAMN05421784_12833 | Hypothetical protein; Belongs to the UPF0250 family. | Negative regulator of replication initiation SeqA; Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated. | 0.492 |
SFU63487.1 | zapD | SAMN05421784_1167 | SAMN05421784_12044 | Hypothetical protein; Belongs to the UPF0250 family. | Cell division protein ZapD; Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity. | 0.519 |
SFU63504.1 | SFU63487.1 | SAMN05421784_1168 | SAMN05421784_1167 | Penicillin-binding protein 6. Serine peptidase. MEROPS family S11; Belongs to the peptidase S11 family. | Hypothetical protein; Belongs to the UPF0250 family. | 0.561 |
SFU63504.1 | lptE | SAMN05421784_1168 | SAMN05421784_11616 | Penicillin-binding protein 6. Serine peptidase. MEROPS family S11; Belongs to the peptidase S11 family. | LPS-assembly lipoprotein; Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane. | 0.408 |
fadR | SFU63487.1 | SAMN05421784_1574 | SAMN05421784_1167 | Transcriptional regulator, GntR family; Multifunctional regulator of fatty acid metabolism. | Hypothetical protein; Belongs to the UPF0250 family. | 0.471 |
fadR | mutH | SAMN05421784_1574 | SAMN05421784_12014 | Transcriptional regulator, GntR family; Multifunctional regulator of fatty acid metabolism. | DNA mismatch repair protein MutH; Sequence-specific endonuclease that cleaves unmethylated GATC sequences. It is involved in DNA mismatch repair. Belongs to the MutH family. | 0.701 |