STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SFU74327.1ABC-type uncharacterized transport system, permease component. (263 aa)    
Predicted Functional Partners:
SFU27250.1
Thiol:disulfide interchange protein DsbC; Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process; Belongs to the thioredoxin family. DsbC subfamily.
 
     0.706
SFU74348.1
Mg2+ and Co2+ transporter CorB, contains DUF21, CBS pair, and CorC-HlyC domains.
  
    0.654
SFU48352.1
Uncharacterized protein.
  
     0.603
SFU39935.1
Stringent starvation protein B.
  
     0.589
SFU62158.1
Methyltransferase domain-containing protein.
  
     0.586
SFU63650.1
DNA polymerase III, delta subunit.
  
     0.576
SFU41513.1
Hypothetical protein; Belongs to the UPF0352 family.
  
    0.547
lptA
Lipopolysaccharide export system protein LptA; Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm.
  
     0.544
crl
Transcriptional regulator; Binds to the sigma-S subunit of RNA polymerase, activating expression of sigma-S-regulated genes. Stimulates RNA polymerase holoenzyme formation and may bind to several other sigma factors, such as sigma-70 and sigma-32; Belongs to the Crl family.
  
     0.528
ffh
Signal recognition particle subunit FFH/SRP54 (srp54); Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the i [...]
       0.528
Your Current Organism:
Xenorhabdus koppenhoeferi
NCBI taxonomy Id: 351659
Other names: CIP 109199, DSM 18168, X. koppenhoeferi, Xenorhabdus koppenhoeferi Tailliez et al. 2006, Xenorhabdus sp. USNJ01, strain USNJ01
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