Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ppdDPrepilin peptidase-dependent protein D. (140 aa)    
Predicted Functional Partners:
hofB
Protein transport protein hofB.
 
  
 0.827
hofC
Component in type IV pilin biogenesis, transmembrane protein.
 
   
 0.818
XDD1_0072
Putative transport protein, possibly in biosynthesis of type IV pilin; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.
 
   
 0.637
XDD1_2768
Homologs of previously reported genes of unknown function.
  
     0.602
XDD1_2978
Homologs of previously reported genes of unknown function; Belongs to the UPF0149 family.
  
     0.591
XDD1_1161
Bifunctional prepilin peptidase: leader peptidase; methyl transferase (General Secretory Pathway); Belongs to the peptidase A24 family.
 
   
 0.578
zapD
Conserved protein of unknown function; Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity.
 
     0.565
ampD
1,6-anhydro-N-acetylmuramyl-L-alanine amidase AmpD.
 
   
 0.550
XDD1_0185
Homologs of previously reported genes of unknown function.
  
     0.519
coaE
Dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family.
       0.507
Your Current Organism:
Xenorhabdus doucetiae
NCBI taxonomy Id: 351671
Other names: CIP 109074, DSM 17909, X. doucetiae, Xenorhabdus doucetiae Tailliez et al. 2006, Xenorhabdus sp. FRG30, strain FRM16
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.