STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ptsNNitrogen regulatory protein. (155 aa)    
Predicted Functional Partners:
ptsO
Phosphocarrier protein NPr.
 
 
 0.985
rapZ
Conserved protein of unknown function; Modulates the synthesis of GlmS, by affecting the processing and stability of the regulatory small RNA GlmZ. When glucosamine-6- phosphate (GlcN6P) concentrations are high in the cell, RapZ binds GlmZ and targets it to cleavage by RNase E. Consequently, GlmZ is inactivated and unable to activate GlmS synthesis. Under low GlcN6P concentrations, RapZ is sequestered and inactivated by an other regulatory small RNA, GlmY, preventing GlmZ degradation and leading to synthesis of GlmS; Belongs to the RapZ-like family. RapZ subfamily.
  
  
 0.910
rpoN
RNA polymerase sigma-54 factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
 
  
 0.877
yhbH
Putative sigma(54) modulation protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.
 
  
 0.861
ptsP
Phosphoenolpyruvate-protein phosphotransferase ptsP; Belongs to the PEP-utilizing enzyme family.
  
   
 0.760
fruK
1-phosphofructokinase; Belongs to the carbohydrate kinase PfkB family.
 
  
 0.744
ptsI
Phosphoenolpyruvate-protein phosphotransferase; General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).
 
  
 0.741
manX
PTS system mannose-specific EIIAB component [Includes: Mannose-specific phosphotransferase enzyme IIA component; Mannose-specific phosphotransferase enzyme IIB component].
 
  
 0.737
raiA
Ribosome-associated inhibitor A.
  
  
 0.690
murP
PTS system N-acetylmuramic acid-specific EIIBC component [Includes: N-acetylmuramic acid-specific phosphotransferase enzyme IIB component; N-acetylmuramic acid permease IIC component].
  
  
 0.633
Your Current Organism:
Xenorhabdus doucetiae
NCBI taxonomy Id: 351671
Other names: CIP 109074, DSM 17909, X. doucetiae, Xenorhabdus doucetiae Tailliez et al. 2006, Xenorhabdus sp. FRG30, strain FRM16
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