STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KLU15251.1Transcriptional regulator; Binds to the purF operator and coregulates other genes for de novo purine nucleotide synthesis; is involved in regulation of purB, purC, purEK, purHD, purL, purMN and guaBA expression; binds hypoxanthine and guanine as inducers; Derived by automated computational analysis using gene prediction method: Protein Homology. (341 aa)    
Predicted Functional Partners:
gltB
Catalyzes the formation of glutamate from glutamine and alpha-ketoglutarate; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 
 0.901
KLU15819.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 
 0.859
KLU14835.1
PTS N-acetyl glucosamine transporter subunits IIABC; Phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.828
KLU17251.1
PTS system trehalose(maltose)-specific transporter subunits IIBC; Phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.791
guaA
GMP synthase; Contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
   0.664
KLU16652.1
PTS sugar transporter; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 
 0.650
KLU15878.1
Phosphohistidinoprotein-hexose phosphotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 
 0.647
KLU13917.1
PTS sugar transporter subunit IIA; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 
 0.602
KLU16363.1
Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 
 0.589
KLU14838.1
Transcriptional regulator; Regulates the synthesis of glucosamine and N-acetylglucosamine by acting as a repressor of the nagEBACD operon and both a repressor and activator of the glmSU operon; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.577
Your Current Organism:
Xenorhabdus griffiniae
NCBI taxonomy Id: 351672
Other names: CIP 109073, DSM 17911, X. griffiniae, Xenorhabdus griffiniae Tailliez et al. 2006, Xenorhabdus sp. ID10, strain ID10
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