node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SFJ02790.1 | SFJ02825.1 | SAMN05421680_10552 | SAMN05421680_10553 | Magnesium transporter; Acts as a magnesium transporter. | Exopolyphosphatase / guanosine-5'-triphosphate,3'-diphosphate pyrophosphatase; Belongs to the GppA/Ppx family. | 0.566 |
SFJ02790.1 | SFJ41992.1 | SAMN05421680_10552 | SAMN05421680_1093 | Magnesium transporter; Acts as a magnesium transporter. | Glutamate synthase (NADPH) large subunit. | 0.663 |
SFJ02790.1 | SFJ63994.1 | SAMN05421680_10552 | SAMN05421680_11285 | Magnesium transporter; Acts as a magnesium transporter. | XTP/dITP diphosphohydrolase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | 0.655 |
SFJ02790.1 | SFJ93263.1 | SAMN05421680_10552 | SAMN05421680_12041 | Magnesium transporter; Acts as a magnesium transporter. | Hypoxanthine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.644 |
SFJ02790.1 | guaA | SAMN05421680_10552 | SAMN05421680_10588 | Magnesium transporter; Acts as a magnesium transporter. | GMP synthase (glutamine-hydrolysing); Catalyzes the synthesis of GMP from XMP. | 0.827 |
SFJ02790.1 | guaB | SAMN05421680_10552 | SAMN05421680_10587 | Magnesium transporter; Acts as a magnesium transporter. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.719 |
SFJ02790.1 | ppk | SAMN05421680_10552 | SAMN05421680_10554 | Magnesium transporter; Acts as a magnesium transporter. | Polyphosphate kinase; Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP). Belongs to the polyphosphate kinase 1 (PPK1) family. | 0.614 |
SFJ02790.1 | purA | SAMN05421680_10552 | SAMN05421680_103264 | Magnesium transporter; Acts as a magnesium transporter. | Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | 0.688 |
SFJ02790.1 | purH | SAMN05421680_10552 | SAMN05421680_12646 | Magnesium transporter; Acts as a magnesium transporter. | IMP cyclohydrolase. | 0.672 |
SFJ02790.1 | surE | SAMN05421680_10552 | SAMN05421680_12720 | Magnesium transporter; Acts as a magnesium transporter. | 5'-nucleotidase /3'-nucleotidase; Nucleotidase with a broad substrate specificity as it can dephosphorylate various ribo- and deoxyribonucleoside 5'-monophosphates and ribonucleoside 3'-monophosphates with highest affinity to 3'-AMP. Also hydrolyzes polyphosphate (exopolyphosphatase activity) with the preference for short-chain-length substrates (P20-25). Might be involved in the regulation of dNTP and NTP pools, and in the turnover of 3'-mononucleotides produced by numerous intracellular RNases (T1, T2, and F) during the degradation of various RNAs. | 0.692 |
SFJ02825.1 | SFJ02790.1 | SAMN05421680_10553 | SAMN05421680_10552 | Exopolyphosphatase / guanosine-5'-triphosphate,3'-diphosphate pyrophosphatase; Belongs to the GppA/Ppx family. | Magnesium transporter; Acts as a magnesium transporter. | 0.566 |
SFJ02825.1 | ppk | SAMN05421680_10553 | SAMN05421680_10554 | Exopolyphosphatase / guanosine-5'-triphosphate,3'-diphosphate pyrophosphatase; Belongs to the GppA/Ppx family. | Polyphosphate kinase; Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP). Belongs to the polyphosphate kinase 1 (PPK1) family. | 0.985 |
SFJ41992.1 | SFJ02790.1 | SAMN05421680_1093 | SAMN05421680_10552 | Glutamate synthase (NADPH) large subunit. | Magnesium transporter; Acts as a magnesium transporter. | 0.663 |
SFJ41992.1 | SFJ63994.1 | SAMN05421680_1093 | SAMN05421680_11285 | Glutamate synthase (NADPH) large subunit. | XTP/dITP diphosphohydrolase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | 0.724 |
SFJ41992.1 | SFJ93263.1 | SAMN05421680_1093 | SAMN05421680_12041 | Glutamate synthase (NADPH) large subunit. | Hypoxanthine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.798 |
SFJ41992.1 | guaA | SAMN05421680_1093 | SAMN05421680_10588 | Glutamate synthase (NADPH) large subunit. | GMP synthase (glutamine-hydrolysing); Catalyzes the synthesis of GMP from XMP. | 0.932 |
SFJ41992.1 | guaB | SAMN05421680_1093 | SAMN05421680_10587 | Glutamate synthase (NADPH) large subunit. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.907 |
SFJ41992.1 | purA | SAMN05421680_1093 | SAMN05421680_103264 | Glutamate synthase (NADPH) large subunit. | Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | 0.746 |
SFJ41992.1 | purH | SAMN05421680_1093 | SAMN05421680_12646 | Glutamate synthase (NADPH) large subunit. | IMP cyclohydrolase. | 0.823 |
SFJ63994.1 | SFJ02790.1 | SAMN05421680_11285 | SAMN05421680_10552 | XTP/dITP diphosphohydrolase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | Magnesium transporter; Acts as a magnesium transporter. | 0.655 |