node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SFI79998.1 | SFK00420.1 | SAMN05421680_103302 | SAMN05421680_12348 | ATP-dependent DNA helicase UvrD. | DNA polymerase III, alpha subunit. | 0.408 |
SFI79998.1 | ligA | SAMN05421680_103302 | SAMN05421680_102190 | ATP-dependent DNA helicase UvrD. | DNA ligase (NAD+); DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA; Belongs to the NAD-dependent DNA ligase family. LigA subfamily. | 0.603 |
SFI79998.1 | ligB | SAMN05421680_103302 | SAMN05421680_10646 | ATP-dependent DNA helicase UvrD. | DNA ligase (NAD+); Catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. Belongs to the NAD-dependent DNA ligase family. LigB subfamily. | 0.581 |
SFI79998.1 | polA | SAMN05421680_103302 | SAMN05421680_12432 | ATP-dependent DNA helicase UvrD. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.678 |
SFI79998.1 | topA | SAMN05421680_103302 | SAMN05421680_104208 | ATP-dependent DNA helicase UvrD. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.535 |
SFJ79209.1 | SFK00420.1 | SAMN05421680_11651 | SAMN05421680_12348 | DNA polymerase III, delta prime subunit. | DNA polymerase III, alpha subunit. | 0.985 |
SFJ79209.1 | dnaX | SAMN05421680_11651 | SAMN05421680_10754 | DNA polymerase III, delta prime subunit. | DNA polymerase III, gamma subunit /DNA polymerase III, tau subunit; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. | 0.992 |
SFJ79209.1 | ligA | SAMN05421680_11651 | SAMN05421680_102190 | DNA polymerase III, delta prime subunit. | DNA ligase (NAD+); DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA; Belongs to the NAD-dependent DNA ligase family. LigA subfamily. | 0.520 |
SFJ79209.1 | ligB | SAMN05421680_11651 | SAMN05421680_10646 | DNA polymerase III, delta prime subunit. | DNA ligase (NAD+); Catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. Belongs to the NAD-dependent DNA ligase family. LigB subfamily. | 0.559 |
SFJ79209.1 | polA | SAMN05421680_11651 | SAMN05421680_12432 | DNA polymerase III, delta prime subunit. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.945 |
SFJ79209.1 | topA | SAMN05421680_11651 | SAMN05421680_104208 | DNA polymerase III, delta prime subunit. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.505 |
SFK00420.1 | SFI79998.1 | SAMN05421680_12348 | SAMN05421680_103302 | DNA polymerase III, alpha subunit. | ATP-dependent DNA helicase UvrD. | 0.408 |
SFK00420.1 | SFJ79209.1 | SAMN05421680_12348 | SAMN05421680_11651 | DNA polymerase III, alpha subunit. | DNA polymerase III, delta prime subunit. | 0.985 |
SFK00420.1 | dnaX | SAMN05421680_12348 | SAMN05421680_10754 | DNA polymerase III, alpha subunit. | DNA polymerase III, gamma subunit /DNA polymerase III, tau subunit; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. | 0.987 |
SFK00420.1 | leuS | SAMN05421680_12348 | SAMN05421680_11836 | DNA polymerase III, alpha subunit. | leucyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. | 0.417 |
SFK00420.1 | ligA | SAMN05421680_12348 | SAMN05421680_102190 | DNA polymerase III, alpha subunit. | DNA ligase (NAD+); DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA; Belongs to the NAD-dependent DNA ligase family. LigA subfamily. | 0.568 |
SFK00420.1 | ligB | SAMN05421680_12348 | SAMN05421680_10646 | DNA polymerase III, alpha subunit. | DNA ligase (NAD+); Catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. Belongs to the NAD-dependent DNA ligase family. LigB subfamily. | 0.562 |
SFK00420.1 | polA | SAMN05421680_12348 | SAMN05421680_12432 | DNA polymerase III, alpha subunit. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.667 |
SFK00420.1 | topA | SAMN05421680_12348 | SAMN05421680_104208 | DNA polymerase III, alpha subunit. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.474 |
dnaX | SFJ79209.1 | SAMN05421680_10754 | SAMN05421680_11651 | DNA polymerase III, gamma subunit /DNA polymerase III, tau subunit; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. | DNA polymerase III, delta prime subunit. | 0.992 |