node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
EFB89684.1 | EFB90081.1 | HMPREF7215_2419 | HMPREF7215_0974 | Malic enzyme, NAD binding domain protein; Identified by match to protein family HMM PF00390; match to protein family HMM PF03949. | Threonine/alanine tRNA ligase second additional domain protein; Identified by match to protein family HMM PF07973. | 0.632 |
EFB89684.1 | alaS | HMPREF7215_2419 | HMPREF7215_0626 | Malic enzyme, NAD binding domain protein; Identified by match to protein family HMM PF00390; match to protein family HMM PF03949. | alanine--tRNA ligase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain. | 0.632 |
EFB90081.1 | EFB89684.1 | HMPREF7215_0974 | HMPREF7215_2419 | Threonine/alanine tRNA ligase second additional domain protein; Identified by match to protein family HMM PF07973. | Malic enzyme, NAD binding domain protein; Identified by match to protein family HMM PF00390; match to protein family HMM PF03949. | 0.632 |
EFB90081.1 | EFB90082.1 | HMPREF7215_0974 | HMPREF7215_0976 | Threonine/alanine tRNA ligase second additional domain protein; Identified by match to protein family HMM PF07973. | Hypothetical protein; Identified by glimmer; putative. | 0.773 |
EFB90081.1 | EFB91072.1 | HMPREF7215_0974 | HMPREF7215_0664 | Threonine/alanine tRNA ligase second additional domain protein; Identified by match to protein family HMM PF07973. | CDP-glycerol:poly(glycerophosphate) glycerophosphotransferase; Identified by match to protein family HMM PF04464. | 0.987 |
EFB90081.1 | alaS | HMPREF7215_0974 | HMPREF7215_0626 | Threonine/alanine tRNA ligase second additional domain protein; Identified by match to protein family HMM PF07973. | alanine--tRNA ligase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain. | 0.808 |
EFB90081.1 | aspS | HMPREF7215_0974 | HMPREF7215_0750 | Threonine/alanine tRNA ligase second additional domain protein; Identified by match to protein family HMM PF07973. | aspartate--tRNA ligase; Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn); Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily. | 0.670 |
EFB90081.1 | ileS | HMPREF7215_0974 | HMPREF7215_2480 | Threonine/alanine tRNA ligase second additional domain protein; Identified by match to protein family HMM PF07973. | isoleucine--tRNA ligase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily. | 0.683 |
EFB90081.1 | leuS | HMPREF7215_0974 | HMPREF7215_2670 | Threonine/alanine tRNA ligase second additional domain protein; Identified by match to protein family HMM PF07973. | leucine--tRNA ligase; Identified by match to protein family HMM PF00133; match to protein family HMM PF08264; match to protein family HMM PF09334; match to protein family HMM TIGR00396; Belongs to the class-I aminoacyl-tRNA synthetase family. | 0.675 |
EFB90081.1 | metG | HMPREF7215_0974 | HMPREF7215_0932 | Threonine/alanine tRNA ligase second additional domain protein; Identified by match to protein family HMM PF07973. | methionine--tRNA ligase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. | 0.844 |
EFB90081.1 | pheT | HMPREF7215_0974 | HMPREF7215_0514 | Threonine/alanine tRNA ligase second additional domain protein; Identified by match to protein family HMM PF07973. | phenylalanine--tRNA ligase, beta subunit; Identified by match to protein family HMM PF01588; match to protein family HMM PF03147; match to protein family HMM PF03483; match to protein family HMM PF03484; match to protein family HMM TIGR00472; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. | 0.814 |
EFB90081.1 | valS | HMPREF7215_0974 | HMPREF7215_0567 | Threonine/alanine tRNA ligase second additional domain protein; Identified by match to protein family HMM PF07973. | valine--tRNA ligase; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner; Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily. | 0.762 |
EFB90082.1 | EFB90081.1 | HMPREF7215_0976 | HMPREF7215_0974 | Hypothetical protein; Identified by glimmer; putative. | Threonine/alanine tRNA ligase second additional domain protein; Identified by match to protein family HMM PF07973. | 0.773 |
EFB91072.1 | EFB90081.1 | HMPREF7215_0664 | HMPREF7215_0974 | CDP-glycerol:poly(glycerophosphate) glycerophosphotransferase; Identified by match to protein family HMM PF04464. | Threonine/alanine tRNA ligase second additional domain protein; Identified by match to protein family HMM PF07973. | 0.987 |
EFB91072.1 | alaS | HMPREF7215_0664 | HMPREF7215_0626 | CDP-glycerol:poly(glycerophosphate) glycerophosphotransferase; Identified by match to protein family HMM PF04464. | alanine--tRNA ligase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain. | 0.987 |
alaS | EFB89684.1 | HMPREF7215_0626 | HMPREF7215_2419 | alanine--tRNA ligase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain. | Malic enzyme, NAD binding domain protein; Identified by match to protein family HMM PF00390; match to protein family HMM PF03949. | 0.632 |
alaS | EFB90081.1 | HMPREF7215_0626 | HMPREF7215_0974 | alanine--tRNA ligase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain. | Threonine/alanine tRNA ligase second additional domain protein; Identified by match to protein family HMM PF07973. | 0.808 |
alaS | EFB91072.1 | HMPREF7215_0626 | HMPREF7215_0664 | alanine--tRNA ligase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain. | CDP-glycerol:poly(glycerophosphate) glycerophosphotransferase; Identified by match to protein family HMM PF04464. | 0.987 |
alaS | aspS | HMPREF7215_0626 | HMPREF7215_0750 | alanine--tRNA ligase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain. | aspartate--tRNA ligase; Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn); Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily. | 0.881 |
alaS | ileS | HMPREF7215_0626 | HMPREF7215_2480 | alanine--tRNA ligase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain. | isoleucine--tRNA ligase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily. | 0.683 |