STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cgd7_4070ATPase ASNA1 homolog; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for ins [...] (366 aa)    
Predicted Functional Partners:
cgd6_870
Putative apicomplexan conserved protein.
    
 0.998
cgd7_4730
RAD23p, UB+UBA domains protein.
   
 0.949
Sec61
Putative Sec61 signal peptide plus 9 transmembrane domain-containing protein.
    
 
 0.865
cgd1_2830
Syntaxin 5A ortholog, possible transmembrane domain or GPI at C-terminus; Belongs to the syntaxin family.
   
 0.848
cgd7_4550
Ubiquitin-like protein, putative.
   
 0.844
cgd1_1890
Vesicle transport protein, putative; Belongs to the synaptobrevin family.
   
 
 0.699
cgd7_1640
Signal recognition particle 54 kDa protein; Binds to the signal sequence of presecretory protein when they emerge from the ribosomes and transfers them to TRAM (translocating chain-associating membrane protein). Belongs to the GTP-binding SRP family. SRP54 subfamily.
     
 0.689
cgd2_620
Uncharacterized protein.
    
 0.681
cgd6_4060
Uncharacterized protein.
    
 
 0.664
cgd5_2550
Polyubiquitin with 3 Ub domains.
    
 0.657
Your Current Organism:
Cryptosporidium parvum
NCBI taxonomy Id: 353152
Other names: C. parvum Iowa II, Cryptosporidium parvum Iowa II, Cryptosporidium parvum strain Iowa type II
Server load: low (8%) [HD]