STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Q4CRF3_TRYCCProtein kinase, putative; Belongs to the protein kinase superfamily. (294 aa)    
Predicted Functional Partners:
Q4DY61_TRYCC
DNA repair and transcription factor protein, putative.
   
 0.698
Q4DWU1_TRYCC
DNA-directed RNA polymerase II subunit 3, putative.
   
 0.613
Q4CRQ2_TRYCC
DNA-directed RNA polymerase II subunit 2, putative; Belongs to the RNA polymerase beta chain family.
    
  0.555
Q4DCA7_TRYCC
DNA-directed RNA polymerases I, II, and III subunit RPABC3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non- coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively.
   
  0.552
Q4CMV3_TRYCC
TFIIH basal transcription factor complex helicase subunit, putative.
    
 0.548
Q4CZ36_TRYCC
TFIIH basal transcription factor complex helicase subunit, putative.
    
 0.548
Q4E4P5_TRYCC
DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
  0.531
Q4DF86_TRYCC
General transcription factor IIH subunit 4; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family.
    
 0.517
Q4DHY8_TRYCC
General transcription factor IIH subunit 4; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family.
    
 0.517
Q4D5K3_TRYCC
DNA repair helicase, putative.
    
 0.492
Your Current Organism:
Trypanosoma cruzi
NCBI taxonomy Id: 353153
Other names: T. cruzi strain CL Brener, Trypanosoma cruzi strain CL Brener
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.