STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Q4DSR2_TRYCCATP-dependent (S)-NAD(P)H-hydrate dehydratase; Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ATP, which is converted to ADP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S-and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Belongs to the NnrE/AIBP family. (595 aa)    
Predicted Functional Partners:
Q4D5E7_TRYCC
ATP-dependent DEAD/H RNA helicase, putative.
  
 0.967
Q4DC77_TRYCC
ATP-dependent DEAD/H RNA helicase, putative.
  
 0.967
Q4DIE1_TRYCC
ATP-dependent DEAD/H RNA helicase, putative; Belongs to the DEAD box helicase family.
  
 0.967
Q4E1M8_TRYCC
Uncharacterized protein.
    
 
 0.886
LSM4
U6 snRNA-associated Sm-like protein LSm4; Binds specifically to the 3'-terminal U-tract of U6 snRNA.
   
 0.819
LSM4-2
U6 snRNA-associated Sm-like protein LSm4; Binds specifically to the 3'-terminal U-tract of U6 snRNA.
   
 0.819
Q4CU80_TRYCC
NUDIX hydrolase, putative.
  
 0.814
Q4D5V9_TRYCC
NUDIX hydrolase, putative.
  
 0.814
Q4D8Y8_TRYCC
Nudix hydrolase domain-containing protein.
  
 0.814
Q4DB19_TRYCC
Nudix hydrolase, putative.
  
 0.814
Your Current Organism:
Trypanosoma cruzi
NCBI taxonomy Id: 353153
Other names: T. cruzi strain CL Brener, Trypanosoma cruzi strain CL Brener
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